Bus Tickets from Biloxi, MS to Chicago, IL

Find affordable bus tickets from Biloxi, MS to Chicago, IL with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayApr 28
from US$226
TomorrowApr 29
WedApr 30
ThuMay 1
FriMay 2
SatMay 3
SunMay 4
MonMay 5

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: April 28 at
    Departure city: Biloxi
    Departure location: BILOXI
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: April 28 at
    Departure city: Biloxi
    Departure location: BILOXI
    Arrival time: April 29 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 28 at
    Departure city: Biloxi
    Departure location: BILOXI
    Arrival time: April 29 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 8:04 AM CDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Biloxi to Chicago: Trip Overview

Average Ticket PriceUS$261
Average Bus Trip Duration1d 3h
Number of daily buses6
Earliest bus departure10:30am
Distance1281 km
Latest bus departure3:05pm

Biloxi to Chicago Bus

Busbud helps you find a bus from Biloxi to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Biloxi to Chicago from the most reliable bus companies operating this trip.

Discover how much the bus trip from Biloxi to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Biloxi - Chicago

  1. How long is the trip from Biloxi to Chicago by bus?

    The typical travel time from Biloxi to Chicago by bus is around 1d 3h. The fastest bus on this trip will get to Chicago in 1d

  2. What is the travel distance from Biloxi to Chicago?

    The distance between Biloxi and Chicago is around 1280 km (794 miles).

  3. What are the departure and arrival locations for buses traveling from Biloxi to Chicago?

    Buses traveling this route start their trip at Love's, in Biloxi, and end it at Downtown Greyhound Station, in Chicago.

  4. What is the cheapest way to go from Biloxi to Chicago?

    Taking the bus is the cheapest option to travel from Biloxi to Chicago. Starting at US$123, this bus is the most cost-effective option for your journey.

  5. How much does the bus ticket cost from Biloxi to Chicago?

    Taking the bus from Biloxi to Chicago costs on average US$261.

  6. Is there an overnight bus from Biloxi to Chicago?

    Yes! Catch buses leaving from Biloxi until 3:05pm and reaching Chicago on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-26
No data
04-27
No data
Today
US$218
04-29
No data
04-30
No data
05-01
No data
05-02
No data
05-03
US$123
busbud logoThe cheapest trip from Biloxi to Chicago was searched and found on May 3, 2025 with a price of US$123

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Biloxi to Chicago, as early as possible.

You can expect to pay from US$123 to US$230 for a bus ticket from Biloxi to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$123 which is on 2025-05-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Biloxi and Chicago!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Biloxi to Chicago, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Biloxi to Chicago will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Biloxi to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Biloxi by bus?

Bus from Biloxi to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Biloxi

Buses Leaving from Biloxi

Buses Going to Biloxi

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago