Bus Tickets from Chicago, IL to Panama City, FL

Find affordable bus tickets from Chicago, IL to Panama City, FL with flexible options. Book your trip now

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TodayJan 22
TomorrowJan 23
from US$196
FriJan 24
SatJan 25
SunJan 26
MonJan 27
TueJan 28
WedJan 29

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: January 23 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: January 24 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: January 23 at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: January 24 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: January 23 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: January 24 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: January 23 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: January 25 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: January 23 at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: January 24 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 3:09 AM CST.

Prices and availability are subject to change.

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Bus Chicago to Panama City: Trip Overview

Average Ticket PriceUS$276
Average Bus Trip Duration1d 6h
Number of daily buses1
Earliest bus departure6:10am
Distance1310 km
Latest bus departure11:50pm

Chicago to Panama City Buses

With Busbud, comparing and booking tickets for a bus from Chicago to Panama City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Chicago to Panama City will be provided by the most trusted bus companies.

Discover how much the bus trip from Chicago to Panama City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Chicago - Panama City

  1. How long is the trip from Chicago to Panama City by bus?

    The bus ride from Chicago to Panama City takes 1d 6h, on average. The fastest bus on this trip will get to Panama City in 1d 3h

  2. What is the travel distance from Chicago to Panama City?

    Chicago and Panama City are 1314 km (815 miles) apart.

  3. How many buses make the trip between Chicago and Panama City each day?

    There's a daily bus trip from Chicago to Panama City. It's offered by Greyhound and usually departs at 6:10am.

  4. What time does the first bus depart from Chicago to Panama City, and when is the last one?

    You can catch the bus at 6:10am for the first departure, and it runs until 11:50pm for the final departure. If you want a smooth trip, it's a good idea to arrive at the station early to check-in.

  5. What are the departure and arrival locations for buses traveling from Chicago to Panama City?

    Buses departing from Downtown Greyhound Station in Chicago will take you to Panama City Greyhound Bus Station in Panama City.

  6. What is the cheapest way to get from Chicago to Panama City?

    Taking the bus is the cheapest option to travel from Chicago to Panama City. The ticket price for this bus starts at US$134, making this your best choice for this trip.

  7. How much does the bus ticket cost from Chicago to Panama City?

    The bus from Chicago to Panama City will cost you US$276, on average.

  8. Is there an overnight bus from Chicago to Panama City?

    Yes! If you're heading from Chicago to Panama City, you'll find buses departing until 11:50pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01-20
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01-21
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Today
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01-23
US$188
01-24
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%{brand}s logoThe cheapest trip from Chicago to Panama City was searched and found on Jan 23, 2025 with a price of US$188

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Panama City, as early as possible.

You can expect to pay from US$188 to US$244 for a bus ticket from Chicago to Panama City based on the last 2 days. You can expect to find the cheapest price for the trip at US$188 which is on 2025-01-23.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Chicago to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Chicago to Panama City, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Chicago to Panama City will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Chicago to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Chicago by bus?

Bus from Chicago to Panama City

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