Bus Tickets from Columbia, MO to Chicago, IL

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TodayApr 12
from US$159
TomorrowApr 13
MonApr 14
TueApr 15
WedApr 16
from US$64
ThuApr 17
FriApr 18
SatApr 19

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: April 16 at
    Departure city: Columbia
    Departure location: Columbia Wabash Station
    Arrival time: April 17 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: April 16 at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: April 16 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 16 at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: April 16 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 16 at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: April 17 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 16 at
    Departure city: Columbia
    Departure location: Midway Truck Plaza Bus Stop
    Arrival time: April 17 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 12:44 PM CDT.

Prices and availability are subject to change.

Accepted payments

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Bus Columbia to Chicago: Trip Overview

Average Ticket PriceUS$73
Average Bus Trip Duration17h 40m
Number of daily buses9
Earliest bus departure8:30am
Distance518 km
Latest bus departure8:35pm

Columbia to Chicago Buses

With Busbud, comparing and booking tickets for a bus from Columbia to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Columbia to Chicago will be provided by the most trusted bus companies.

Discover how much the bus trip from Columbia to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Columbia - Chicago

  1. How long is the trip from Columbia to Chicago by bus?

    The typical travel time from Columbia to Chicago by bus is around 17h 40m. The fastest bus on this trip will get to Chicago in 9h 30m

  2. What is the travel distance from Columbia to Chicago?

    The distance covered from Columbia to Chicago is 512 km (318 miles).

  3. What are the departure and arrival locations for buses traveling from Columbia to Chicago?

    Buses traveling this route start their trip at Midway Truck Plaza Bus Stop, in Columbia, and end it at Downtown Greyhound Station, in Chicago.

  4. What is the cheapest way to go from Columbia to Chicago?

    Taking the bus is the most budget-friendly option to travel from Columbia to Chicago. With a starting ticket price of US$48, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Columbia to Chicago?

    The bus fare from Columbia to Chicago is approximately US$73.

  6. Is there an overnight bus from Columbia to Chicago?

    Yes! Catch buses leaving from Columbia until 8:35pm and reaching Chicago on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-10
US$82
04-11
US$70
Today
US$102
04-13
No data
04-14
US$46
04-15
No data
04-16
US$56
04-17
US$46
busbud logoThe cheapest trip from Columbia to Chicago was searched and found on Apr 14, 2025 with a price of US$46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbia to Chicago, as early as possible.

You can expect to pay from US$46 to US$216 for a bus ticket from Columbia to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$46 which is on 2025-04-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Columbia to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Columbia to Chicago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Columbia to Chicago will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Columbia to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Columbia by bus?

Bus from Columbia to Chicago

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