Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Des Moines (Subway) | Detroit Bus Station | No tags | |||||
FlixBus + Greyhound | Des Moines (Subway) | Detroit Bus Station | No tags | |||||
Greyhound + FlixBus | Des Moines (Subway) | Detroit Bus Station | No tags | |||||
| Des Moines (Subway) | Detroit Bus Station | No tags | |||||
| Des Moines (Subway) | Detroit Bus Station | No tags |
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Bus Des Moines to Detroit, MI: Trip Overview
Compare bus companies
Based on 87264 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$97
Des Moines to Detroit Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Des Moines to Detroit.
We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to Detroit.
From cheap bus tickets to more luxurious buses travelling from Des Moines to Detroit, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Des Moines and Detroit?
Frequently asked questions on the trip Des Moines - Detroit, MI
What is the distance between Des Moines and Detroit?
The distance between Des Moines and Detroit is around 878 km (545 miles).
What are the departure and arrival locations for buses traveling from Des Moines to Detroit?
Buses traveling this route start their trip at Jefferson/Trailways Depot, in Des Moines, and end it at Detroit Bus Station, in Detroit.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Detroit, MI was searched and found on Sep 17, 2025 with a price of US$106To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Detroit, MI, as early as possible.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Des Moines to Detroit but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Des Moines to Detroit.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Detroit that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Des Moines to Detroit, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top travelled bus routes
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Popular Buses Connecting Des Moines
Buses Leaving from Des Moines
- Bus from Des Moines to Iowa City
- Bus Des Moines - Washington
- Des Moines - Omaha
- Bus from Des Moines to Denver
- Bus Des Moines - Cedar Rapids
- Des Moines - Chicago
- Bus from Des Moines to Jackson
- Bus Des Moines - Ames
- Des Moines - Keokuk
- Bus from Des Moines to Las Vegas
- Bus Des Moines - Gilroy
- Des Moines - Clear Lake
- Bus from Des Moines to San Diego
- Bus Des Moines - Madison
- Des Moines - Cleburne
Buses Going to Des Moines
- Bus from Washington to Des Moines
- Bus Chicago - Des Moines
- Minneapolis - Des Moines
- Bus from Las Vegas to Des Moines
- Bus Staples - Des Moines
- Iowa City - Des Moines
- Bus from Vermillion to Des Moines
- Bus Waterloo - Des Moines
- Newark - Des Moines
- Bus from Cedar Rapids to Des Moines
- Bus Los Angeles - Des Moines
- Ottumwa - Des Moines
- Bus from Latimer to Des Moines
- Bus Portland - Des Moines
- New York City - Des Moines
Popular Buses Connecting Detroit
Buses Leaving from Detroit
- Bus from Detroit to Marathon
- Bus Detroit - Miami
- Detroit - Miami
- Bus from Detroit to Ann Arbor
- Bus Detroit - Boston
- Detroit - Buffalo
- Bus from Detroit to New York City
- Bus Detroit - Grand Rapids
- Detroit - Orlando
- Bus from Detroit to Columbus
- Bus Detroit - Indianapolis
- Detroit - Cleveland
- Bus from Detroit to Toledo
- Bus Detroit - Newark
- Detroit - Holland
Buses Going to Detroit
- Bus from Toronto to Detroit
- Bus Nashville - Detroit
- Windsor - Detroit
- Bus from Buffalo to Detroit
- Bus Olympia - Detroit
- Dearborn - Detroit
- Bus from Chicago to Detroit
- Bus New York City - Detroit
- Philadelphia - Detroit
- Bus from Denver to Detroit
- Bus Columbus - Detroit
- Gary - Detroit
- Bus from Lansing to Detroit
- Bus Cleveland - Detroit
- Toledo - Detroit
Popular routes in this country
- Bus from Boston to New York City
- Bus Washington - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Baton Rouge - New Orleans
- Bus from Albany to New York City
- Bus Los Angeles - San Francisco
- Miami - Orlando
- Bus from Los Angeles to San Diego
- Bus Las Vegas - Los Angeles
- Atlanta - Savannah