Bus Tickets from Des Moines, IA to Greenville, SC

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Bus Des Moines to Greenville: Trip Overview

Average Ticket PriceUS$155
Average Bus Trip Duration1d 5h
Number of daily buses1
Earliest bus departure5:30am
Distance1239 km

Des Moines to Greenville Buses

Busbud helps you find a bus from Des Moines to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Greenville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Des Moines to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Des Moines - Greenville

  1. How long does it take to get to Greenville from Des Moines by bus?

    The trip from Des Moines to Greenville will take on average 1d 5h. For the shortest travel time, select the fastest bus available, which will take you to Greenville in about 1d 5h.

  2. What is the distance between Des Moines and Greenville?

    The distance between Des Moines and Greenville is around 1234 km (765 miles).

  3. How often do buses run from Des Moines to Greenville each day?

    A Greyhound bus travels from Des Moines to Greenville only once a day, at 5:30am. It typically leaves at 5:30am and is operated by Greyhound.

  4. When do the first and last bus leave from Des Moines to Greenville?

    You can catch the first bus starting at 5:30am and the last one until 5:30am. To ensure a smooth trip, consider arriving at the station early for check-in.

  5. What are the departure and arrival locations for buses traveling from Des Moines to Greenville?

    Buses traveling this route start their trip at Jefferson/Trailways Depot, in Des Moines, and end it at Guadalajara Supermarket Bus Stop, in Greenville.

  6. What is the cheapest way to travel from Des Moines to Greenville?

    The least expensive way to go from Des Moines to Greenville would be going by bus. Starting at US$155, this bus is the most cost-effective option for your journey.

  7. How much is the bus from Des Moines to Greenville?

    Taking the bus from Des Moines to Greenville costs on average US$155.

  8. Is it possible to travel by overnight bus from Des Moines to Greenville?

    Yes! Catch buses leaving from Des Moines until 5:30am and reaching Greenville on the following day.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Greenville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Greenville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Des Moines to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Des Moines by bus?

Bus from Des Moines to Greenville

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