Bus Tickets from Lyon to Rome

Find affordable bus tickets from Lyon to Rome with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayApr 25
from US$72
TomorrowApr 26
from US$72
SunApr 27
from US$90
MonApr 28
from US$62
TueApr 29
from US$58
WedApr 30
from US$72
ThuMay 1
from US$52
FriMay 2
from US$72

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: April 26 at
    Departure city: Lyon
    Departure location: Lyon Lyon Perrache Bus Station
    Arrival time: April 27 at
    Destination city: Rome
    Destination location: Rome Tiburtina Bus Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: April 26 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: April 27 at
    Destination city: Rome
    Destination location: Rome Tiburtina Bus Station
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: April 26 at
    Destination city: Rome
    Destination location: Aeroporto Ciampino Airport (CIA)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Lyon
    Departure location: Lyon Lyon Perrache Bus Station
    Arrival time: April 26 at
    Destination city: Rome
    Destination location: Rome Tiburtina Bus Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: April 27 at
    Destination city: Rome
    Destination location: Aeroporto Ciampino Airport (CIA)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 8:01 PM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Lyon to Rome: Trip Overview

Average Ticket PriceUS$86
Average Bus Trip Duration17h 10m
Number of daily buses14
Earliest bus departure1:15am
Distance750 km
Latest bus departure11:59pm

Lyon to Rome Bus

With Busbud, comparing and booking tickets for a bus from Lyon to Rome is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Lyon to Rome will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Lyon to Rome, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Lyon - Rome

  1. How long does it take to get to Rome from Lyon by bus?

    The bus ride from Lyon to Rome takes 17h 10m, on average. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 13h 50m.

  2. What is the distance between Lyon and Rome?

    The distance between Lyon and Rome is approximately 748 km (464 miles).

  3. What are the departure and arrival locations for buses traveling from Lyon to Rome?

    Buses departing from Perrache in Lyon will take you to Rome Tiburtina Bus Station in Rome.

  4. What is the cheapest way to get from Lyon to Rome?

    If you're on a budget, consider traveling by bus to Rome from Lyon; it tends to be more affordable. With a starting ticket price of US$34, this bus becomes your top pick for this journey.

  5. How much is the bus from Lyon to Rome?

    You can expect to pay around US$86 for the bus ride from Lyon to Rome.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-23
US$71
04-24
US$82
Today
US$66
04-26
US$66
04-27
US$82
04-28
US$56
04-29
US$53
04-30
US$65
busbud logoThe cheapest trip from Lyon to Rome was searched and found on Apr 29, 2025 with a price of US$53

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Rome, as early as possible.

You can expect to pay from US$53 to US$271 for a bus ticket from Lyon to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at US$53 which is on 2025-04-29.

Usually Flixbus (FR) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Lyon to Rome.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Lyon to Rome, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Lyon to Rome that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Lyon to Rome, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Lyon by bus?

Bus from Lyon to Rome

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Popular Buses Connecting Lyon

Buses Leaving from Lyon

Buses Going to Lyon

Popular Buses Connecting Rome

Buses Leaving from Rome

Buses Going to Rome