Bus Tickets from Orlando, FL to Key West, FL

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TodayApr 28
from US$96
TomorrowApr 29
WedApr 30
ThuMay 1
FriMay 2
SatMay 3
SunMay 4
MonMay 5

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: April 28 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: April 29 at
    Destination city: Key West
    Destination location: Key West Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 4:00 PM EDT.

Prices and availability are subject to change.

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Bus Orlando to Key West: Trip Overview

Average Ticket PriceUS$65
Average Bus Trip Duration10h 55m
Number of daily buses7
Earliest bus departure12:45am
Distance434 km
Latest bus departure10:35pm

Orlando to Key West Bus

Busbud helps you find a bus from Orlando to Key West. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Orlando to Key West from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Key West from Orlando, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Orlando - Key West

  1. How long is the bus ride from Orlando to Key West?

    The typical travel time from Orlando to Key West by bus is around 10h 55m. The fastest bus on this trip will get to Key West in 9h 25m

  2. How far is Orlando from Key West?

    Orlando and Key West are 445 km (276 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Orlando to Key West?

    Buses departing from Orlando Bus Station in Orlando will take you to Caroline St in Key West.

  4. What is the cheapest way to get from Orlando to Key West?

    The least expensive option to go from Orlando to Key West would be going by bus. With a starting ticket price of US$49, this bus becomes your top pick for this journey.

  5. How much does it cost to take the bus from Orlando to Key West?

    The bus from Orlando to Key West will cost you US$65, on average.

  6. Can I take an overnight bus from Orlando to Key West?

    Yes! If you're heading from Orlando to Key West, you'll find buses departing until 10:35pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-26
No data
04-27
US$59
Today
US$88
04-29
US$47
04-30
US$45
05-01
US$54
05-02
No data
05-03
US$59
busbud logoThe cheapest trip from Orlando to Key West was searched and found on Apr 30, 2025 with a price of US$45

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Key West, as early as possible.

You can expect to pay from US$45 to US$107 for a bus ticket from Orlando to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at US$45 which is on 2025-04-30.

Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Orlando and Key West!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Orlando to Key West, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Orlando to Key West.

Make a music playlist for your bus ride from Orlando to Key West, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Orlando by bus?

Bus from Orlando to Key West

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