Bus Tickets from San Diego, CA to Santa Cruz, CA

Find affordable bus tickets from San Diego, CA to Santa Cruz, CA with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayApr 25
from US$100
TomorrowApr 26
SunApr 27
MonApr 28
TueApr 29
WedApr 30
ThuMay 1
FriMay 2

Next departures to Santa Cruz

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: April 25 at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: April 26 at
    Destination city: Santa Cruz
    Destination location: Santa Cruz, CA
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: April 26 at
    Destination city: Santa Cruz
    Destination location: Santa Cruz, CA
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 1:58 PM PDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus San Diego to Santa Cruz: Trip Overview

Average Ticket PriceUS$96
Average Bus Trip Duration15h 48m
Number of daily buses1
Earliest bus departure9:25pm
Distance648 km

San Diego to Santa Cruz Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Santa Cruz is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from San Diego to Santa Cruz will be provided by the most trusted bus companies.

Discover how much the bus trip from San Diego to Santa Cruz will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Diego - Santa Cruz

  1. How long is the bus ride from San Diego to Santa Cruz?

    The bus ride from San Diego to Santa Cruz takes 15h 48m, on average. For the shortest travel time, select the fastest bus available, which will take you to Santa Cruz in about 14h 47m.

  2. How far is San Diego from Santa Cruz?

    The distance between San Diego and Santa Cruz is approximately 651 km (404 miles).

  3. What are the departure and arrival locations for buses traveling from San Diego to Santa Cruz?

    Buses departing from Mission Valley Sheraton in San Diego will take you to Metro Center Bus Station in Santa Cruz.

  4. What is the cheapest way to travel from San Diego to Santa Cruz?

    Taking the bus is the most budget-friendly option to travel from San Diego to Santa Cruz. Starting at US$82, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from San Diego to Santa Cruz?

    You can expect to pay around US$96 for the bus ride from San Diego to Santa Cruz.

  6. Can I take an overnight bus from San Diego to Santa Cruz?

    Yes! If you're heading from San Diego to Santa Cruz, you'll find buses departing until 9:25pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-23
No data
04-24
No data
Today
US$95
04-26
No data
04-27
No data
04-28
No data
04-29
No data
04-30
No data
busbud logoThe cheapest trip from San Diego to Santa Cruz was searched and found on Apr 25, 2025 with a price of US$95

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Santa Cruz, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Diego to Santa Cruz.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from San Diego to Santa Cruz, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Diego to Santa Cruz will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from San Diego to Santa Cruz, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to San Diego by bus?

Bus from San Diego to Santa Cruz

You can also go to Santa Cruz by train

Train from San Diego to Santa Cruz

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Popular Buses Connecting San Diego

Buses Leaving from San Diego

Buses Going to San Diego

Popular Buses Connecting Santa Cruz

Buses Leaving from Santa Cruz

Buses Going to Santa Cruz