Bus Tickets from Santander to Madrid

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TodayApr 24
from US$43
TomorrowApr 25
from US$43
SatApr 26
from US$43
SunApr 27
from US$43
MonApr 28
from US$43
TueApr 29
from US$30
WedApr 30
from US$34
ThuMay 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: April 25 at
    Departure city: Santander
    Departure location: Santander (Estacion de Autobuses)
    Arrival time: April 25 at
    Destination city: Madrid
    Destination location: Avenida de América Metro
    Operated by: ALSAALSA
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: April 25 at
    Departure city: Santander
    Departure location: Santander (Estacion de Autobuses)
    Arrival time: April 25 at
    Destination city: Madrid
    Destination location: Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
    Operated by: ALSA SupraALSA Supra
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: Santander
    Departure location: Santander (Estacion de Autobuses)
    Arrival time: April 25 at
    Destination city: Madrid
    Destination location: Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
    Operated by: ALSA SupraALSA Supra
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: Santander
    Departure location: Santander (Estacion de Autobuses)
    Arrival time: April 25 at
    Destination city: Madrid
    Destination location: Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4
    Operated by: ALSAALSA
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: Santander
    Departure location: Santander (Estacion de Autobuses)
    Arrival time: April 26 at
    Destination city: Madrid
    Destination location: Madrid (South)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 9:24 AM CEST.

Prices and availability are subject to change.

Accepted payments

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Bus Santander to Madrid: Trip Overview

Average Ticket PriceUS$51
Average Bus Trip Duration5h 40m
Number of daily buses13
Earliest bus departure12:45am
Distance336 km
Latest bus departure6:40pm

Santander to Madrid Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santander to Madrid.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santander to Madrid.

Discover how much the bus trip from Santander to Madrid will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Santander - Madrid

  1. How long is the trip from Santander to Madrid by bus?

    The typical travel time from Santander to Madrid by bus is around 5h 40m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 4h 30m.

  2. What is the travel distance from Santander to Madrid?

    The distance between Santander and Madrid is around 340 km (211 miles).

  3. What are the departure and arrival locations for buses traveling from Santander to Madrid?

    Buses traveling this route start their trip at Calle Navas de Tolosa, 2, in Santander, and end it at Avenida de América Metro, in Madrid.

  4. How much does the bus ticket cost from Santander to Madrid?

    The bus fare from Santander to Madrid is approximately US$51.

  5. Is there an overnight bus from Santander to Madrid?

    Yes! Catch buses leaving from Santander until 6:40pm and reaching Madrid on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-22
US$38
04-23
US$155
Today
US$37
04-25
US$37
04-26
US$37
04-27
US$37
04-28
US$37
04-29
US$25
busbud logoThe cheapest trip from Santander to Madrid was searched and found on Apr 29, 2025 with a price of US$25

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Madrid, as early as possible.

You can expect to pay from US$25 to US$181 for a bus ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at US$25 which is on 2025-04-29.

Usually Flixbus (ES) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santander to Madrid but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santander to Madrid.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santander to Madrid will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Santander to Madrid, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Santander by bus?

Bus from Santander to Madrid

You can also go to Madrid by train

Train from Santander to Madrid

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