Next departures to San Francisco
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: April 29 atDeparture city: BuffaloDeparture location: Depew StationArrival time: May 1 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: Amtrak
Vehicle: BusDuration: - Departure time: April 29 atDeparture city: BuffaloDeparture location: Depew StationArrival time: May 1 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: AmtrakVehicle: BusDuration:
Last refresh of the prices: Yesterday at 1:44 PM EDT.
Prices and availability are subject to change.
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Train Buffalo to San Francisco: Trip Overview
Please note, this information is subject to change
Train companies
Based on 5072 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at US$316.00
Buffalo to San Francisco Train
Busbud helps you find a train from Buffalo to San Francisco. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
We make sure you can find a train service from Buffalo to San Francisco from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to San Francisco from Buffalo, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions on the trip Buffalo - San Francisco
How much does a cheap train ticket from Buffalo to San Francisco cost?
The average train ticket price from Buffalo to San Francisco is US$407. The best way to find cheap train tickets from Buffalo to San Francisco is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Buffalo to San Francisco?
A train trip between Buffalo and San Francisco is around 2d 20h, although the fastest train will take about 2d 20h. This is the time it takes to travel the 3697 km that separates the two cities.
How many daily trains are there between Buffalo and San Francisco?
The number of trains from Buffalo to San Francisco can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Buffalo to San Francisco by comparing and selecting the train that fits your travel style and budget on Busbud.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo to San Francisco was searched and found on Apr 24, 2025 with a price of US$425To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo to San Francisco, as early as possible.
You can expect to pay from US$425 to US$1,907 for a train ticket from Buffalo to San Francisco based on the last 2 days. You can expect to find the cheapest price for the trip at US$425 which is on 2025-04-24.
About Train Travel
Train Travel Tips
There are many train stations in the world, check out the station pages on Busbud to get all information you need.
Regional train? High-speed train? Whichever train to San Francisco you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Buffalo and San Francisco, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Create your real-life musical score by curating a personalized train travel playlist - the perfect accompaniment to your train ride from Buffalo to San Francisco.
Did you know?
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.
One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one travelling between the city and the suburbs.
Top Travelled Train Routes
Why choose Busbud?
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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