Find coaches from Santiago del Estero to Mendoza

Find affordable coach tickets from Santiago del Estero to Mendoza with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today15 Apr
from US$72
Tomorrow16 Apr
from US$72
Thu17 Apr
from US$72
Fri18 Apr
Sat19 Apr
from US$56
Sun20 Apr
Mon21 Apr
Tue22 Apr

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 16 April at
    Departure city: Santiago del Estero
    Departure location: Terminal de Ómnibus de Santiago del Estero
    Arrival time: 17 April at
    Destination city: Mendoza
    Destination location: Mendoza Terminal
    Operated by: AndesmarAndesmar
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Santiago del Estero to Mendoza: Trip Overview

Average ticket priceUS$134
Average bus trip duration16h 23m
Number of daily buses1
Earliest bus departure00:20
Distance446 miles
Latest bus departure16:15

Santiago del Estero to Mendoza Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santiago del Estero to Mendoza.

Bus service from Santiago del Estero to Mendoza will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Mendoza from Santiago del Estero, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Santiago del Estero - Mendoza

  1. How much is the coach fare from Santiago del Estero to Mendoza?

    The prices typically range from US$76 to US$148 on this trip, with the average ticket costing US$134. These prices can change depending on factors like the date, the class and the coach company you choose. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long is the coach ride from Santiago del Estero to Mendoza?

    The coach journey between Santiago del Estero and Mendoza lasts about 16h 23m. The quickest coach journey typically takes 16h 23m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from Santiago del Estero to Mendoza?

    The first coach to Mendoza from Santiago del Estero departs at 00:20. Keep in mind that departure times might change on weekends and holidays.

  4. How far is Mendoza from Santiago del Estero by coach?

    The journey from Santiago del Estero to Mendoza by coach covers an approximate distance of 445 miles (717 km).

  5. What is the best way to go from Santiago del Estero to Mendoza without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

  6. Is there am overnight bus from Santiago del Estero to Mendoza?

    Yes, you can find buses leaving until 16:15 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/04
US$80
14/04
US$70
Today
US$63
16/04
US$80
17/04
US$80
18/04
No data
19/04
US$62
20/04
US$62
busbud logoThe cheapest trip from Santiago del Estero to Mendoza was searched and found on 19 Apr 2025 with a price of US$62

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago del Estero to Mendoza as early as possible.

You can expect to pay from US$62 to US$120 for a bus ticket from Santiago del Estero to Mendoza based on the last 2 days. You can expect to find the cheapest price for the trip at US$62, which is on 2025-04-19.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santiago del Estero to Mendoza but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santiago del Estero to Mendoza, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santiago del Estero to Mendoza.

Tune out to the fine sounds of your best music playlist on your bus trip from Santiago del Estero to Mendoza while indulging in miles on end of beautiful scenic views.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Santiago del Estero by bus?

Bus from Santiago del Estero to Mendoza

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Popular Buses Connecting Santiago del Estero

Buses Leaving from Santiago del Estero

Buses Going to Santiago del Estero

Popular Buses Connecting Mendoza

Buses Leaving from Mendoza

Buses Going to Mendoza