Cheap buses leaving Wednesday
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: April 9 atDeparture city: ChicagoDeparture location: Chicago 95Th & Dan RyanArrival time: April 11 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: April 9 atDeparture city: ChicagoDeparture location: Downtown Greyhound StationArrival time: April 11 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: April 9 atDeparture city: ChicagoDeparture location: Downtown Greyhound StationArrival time: April 11 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: April 9 atDeparture city: ChicagoDeparture location: 537-517 W. Jackson BlvdArrival time: April 11 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: April 9 atDeparture city: ChicagoDeparture location: 537-517 W. Jackson BlvdArrival time: April 12 atDestination city: San DiegoDestination location: Greyhound Bus StopOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
Last refresh of the prices: Today at 5:24 PM CDT.
Prices and availability are subject to change.
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Bus Chicago to San Diego: Trip Overview
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Chicago to San Diego Buses
Busbud helps you find a bus from Chicago to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Chicago to San Diego will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Chicago to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Chicago and San Diego?
Frequently asked questions on the trip Chicago - San Diego
How long does it take to get to San Diego from Chicago by bus?
The typical travel time from Chicago to San Diego by bus is around 2d 11h. For the shortest travel time, select the fastest bus available, which will take you to San Diego in about 2d 1h.
What is the distance between Chicago and San Diego?
The distance covered from Chicago to San Diego is 2788 km (1729 miles).
What are the departure and arrival locations for buses traveling from Chicago to San Diego?
Buses traveling this route start their trip at Downtown Greyhound Station, in Chicago, and end it at Mission Valley Sheraton, in San Diego.
What is the cheapest way to go from Chicago to San Diego?
The least expensive option to go from Chicago to San Diego would be going by bus. The ticket price for this bus starts at US$109, making this your best choice for this trip.
How much is the bus from Chicago to San Diego?
The bus fare from Chicago to San Diego is approximately US$223.
Is it possible to travel by overnight bus from Chicago to San Diego?
Yes! Catch buses leaving from Chicago until 11:50pm and reaching San Diego on the following day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to San Diego was searched and found on Apr 7, 2025 with a price of US$180To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Diego, as early as possible.
You can expect to pay from US$180 to US$480 for a bus ticket from Chicago to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$180 which is on 2025-04-07.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Chicago and San Diego!
Much more than a mere vehicle taking you from Chicago to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to San Diego that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Chicago to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top travelled bus routes
Why choose Busbud?
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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