Bus Tickets from Chicago, IL to San Diego, CA

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TodayFeb 22
from $365
TomorrowFeb 23
from $254
MonFeb 24
from $187
TueFeb 25
from $172
WedFeb 26
ThuFeb 27
FriFeb 28
SatMar 1

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: February 23 at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: February 26 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: February 23 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: February 25 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: February 23 at
    Departure city: Chicago
    Departure location: Downtown Greyhound Station
    Arrival time: February 25 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: February 23 at
    Departure city: Chicago
    Departure location: 537-517 W. Jackson Blvd
    Arrival time: February 25 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: February 23 at
    Departure city: Chicago
    Departure location: Chicago 95Th & Dan Ryan
    Arrival time: February 25 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Chicago to San Diego: Trip Overview

Average ticket price$245
Average bus trip duration2d 12h
Number of daily buses26
Earliest bus departure5:45am
Distance1727 miles (2784 km)
Latest bus departure10:30pm

Chicago to San Diego Buses

Busbud helps you find a bus from Chicago to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Chicago to San Diego will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Chicago to San Diego, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Chicago - San Diego

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
02/20
No data
02/21
$195
Today
$365
02/23
$254
02/24
$187
02/25
$172
02/26
No data
02/27
No data
%{brand}s logoThe cheapest trip from Chicago to San Diego was searched and found on Feb 25, 2025 with a price of $172

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to San Diego, as early as possible.

You can expect to pay from $172 to $456 for a bus ticket from Chicago to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at $172 which is on 2025-02-25.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Chicago and San Diego!

Much more than a mere vehicle taking you from Chicago to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to San Diego that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Chicago to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Chicago by bus?

Bus from Chicago to San Diego

You can also go to San Diego by train

Train from Chicago to San Diego

Why choose Busbud?

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Popular Buses Connecting San Diego

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