Bus Tickets from San Diego, CA to San Francisco, CA

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SatApr 26
from $70
SunApr 27
MonApr 28
from $65
TueApr 29
WedApr 30
ThuMay 1
FriMay 2
SatMay 3

Next departures to San Francisco

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: April 28 at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: April 28 at
    Destination city: San Francisco
    Destination location: Mission St & Fremont St
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: April 28 at
    Departure city: San Diego
    Departure location: UCSD Health La Jolla Station
    Arrival time: April 29 at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: April 28 at
    Departure city: San Diego
    Departure location: San Diego (Old Town-FlixBus)
    Arrival time: April 28 at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: April 28 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: April 28 at
    Destination city: San Francisco
    Destination location: San Francisco Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 28 at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: April 28 at
    Destination city: San Francisco
    Destination location: Mission St & Fremont St
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

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Bus San Diego to San Francisco: Trip Overview

Average ticket price$66
Average bus trip duration13h 40m
Number of daily buses17
Earliest bus departure5:15am
Distance446 miles (718 km)
Latest bus departure9:05pm

San Diego to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from San Diego to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Diego to San Francisco from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to San Francisco from San Diego, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip San Diego - San Francisco

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/22
$82
04/23
$66
Today
$66
04/25
$84
04/26
$70
04/27
$67
04/28
$65
04/29
$56
busbud logoThe cheapest trip from San Diego to San Francisco was searched and found on Apr 29, 2025 with a price of $56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to San Francisco, as early as possible.

You can expect to pay from $56 to $444 for a bus ticket from San Diego to San Francisco based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2025-04-29.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to San Francisco, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to San Francisco.

Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to San Francisco while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from San Diego to San Francisco?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego by bus?

Bus from San Diego to San Francisco

You can also go to San Francisco by train

Train from San Diego to San Francisco

Why choose Busbud?

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