Next departures to San Diego
One passenger / one way
- This trip is recommended because it is: CheapestDeparture time: April 27 atDeparture city: ChicagoDeparture location: Chicago (Union Station), ILArrival time: April 30 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is: FastestDeparture time: April 27 atDeparture city: ChicagoDeparture location: Chicago (Union Station), ILArrival time: April 29 atDestination city: San DiegoDestination location: Old Town San DiegoOperated by: AmtrakVehicle: BusDuration:
- Departure time: April 27 atDeparture city: ChicagoDeparture location: Chicago (Union Station), ILArrival time: April 30 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
- Departure time: April 27 atDeparture city: ChicagoDeparture location: Chicago (Union Station), ILArrival time: April 29 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
- Departure time: April 27 atDeparture city: ChicagoDeparture location: Chicago (Union Station), ILArrival time: April 29 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: BusDuration:
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Train Chicago to San Diego: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5074 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $381.00
Chicago to San Diego Train
Busbud helps you find a train from Chicago to San Diego. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
Train service from Chicago to San Diego will be provided by the most trusted companies.
From train tickets to high-end trains trip from Chicago to San Diego, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Chicago - San Diego
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to San Diego was searched and found on Apr 28, 2025 with a price of $169To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to San Diego, as early as possible.
You can expect to pay from $169 to $1,315 for a train ticket from Chicago to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at $169 which is on 2025-04-28.
About Train Travel
Train Travel Tips
There are many train stations in the world, check it station pages on Busbud to get all information you need.
No matter if you plan to take a regional or high-speed train to San Diego, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
The train emits up to 30x less CO2 for a trip between Chicago and San Diego compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Make a music playlist for your train ride from Chicago to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.
One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!
Top Traveled Train Routes
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Popular Trains Connecting Chicago
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Popular Trains Connecting San Diego
Trains Going to San Diego
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