Bus Tickets from San Diego, CA to Chicago, IL

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SatApr 26
from $231
SunApr 27
from $198
MonApr 28
from $196
TueApr 29
WedApr 30
ThuMay 1
FriMay 2
SatMay 3

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 27 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: April 29 at
    Destination city: Chicago
    Destination location: Chicago 95Th & Dan Ryan
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 27 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 27 at
    Departure city: San Diego
    Departure location: Greyhound Bus Stop
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus San Diego to Chicago: Trip Overview

Average ticket price$237
Average bus trip duration2d 12h
Number of daily buses10
Earliest bus departure7:15am
Distance1728 miles (2787 km)
Latest bus departure7:35pm

San Diego to Chicago Bus

With Busbud, comparing and booking tickets for a bus from San Diego to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Diego to Chicago.

From cheap bus tickets to more luxurious buses traveling from San Diego to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Diego - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/22
No data
04/23
$352
Today
$278
04/25
No data
04/26
$231
04/27
$198
04/28
$196
04/29
No data
busbud logoThe cheapest trip from San Diego to Chicago was searched and found on Apr 28, 2025 with a price of $196

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Chicago, as early as possible.

You can expect to pay from $196 to $493 for a bus ticket from San Diego to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $196 which is on 2025-04-28.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Diego to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from San Diego to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to Chicago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Chicago.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from San Diego to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Diego by bus?

Bus from San Diego to Chicago

You can also go to Chicago by train

Train from San Diego to Chicago

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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