Bus Tickets from Columbia, SC to Panama City, FL

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Frequently asked questions on the trip Columbia - Panama City

  1. What is the distance between Columbia and Panama City?

    Columbia and Panama City are 612 km (379 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Columbia to Panama City?

    Buses departing from Columbia Bus Station in Columbia will take you to Panama City Greyhound Bus Station in Panama City.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Columbia and Panama City!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Columbia to Panama City.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Columbia to Panama City will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Columbia to Panama City while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Columbia by bus?

Bus from Columbia to Panama City

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Popular Buses Connecting Columbia

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Popular Buses Connecting Panama City

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