Bus Tickets from Indianapolis, IN to Des Moines, IA

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TodayApr 25
TomorrowApr 26
from US$93
SunApr 27
MonApr 28
TueApr 29
WedApr 30
ThuMay 1
FriMay 2

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: April 27 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 8:04 PM EDT.

Prices and availability are subject to change.

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Bus Indianapolis to Des Moines: Trip Overview

Average Ticket PriceUS$147
Average Bus Trip Duration18h 5m
Number of daily buses3
Earliest bus departure7:10am
Distance660 km
Latest bus departure9:30pm

Indianapolis to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Des Moines.

Discover how much the bus trip from Indianapolis to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Indianapolis - Des Moines

  1. How long is the bus trip from Indianapolis to Des Moines?

    The trip from Indianapolis to Des Moines will take on average 18h 5m. The fastest bus on this trip will get to Des Moines in 12h

  2. How far is Indianapolis from Des Moines?

    The distance between Indianapolis and Des Moines is around 661 km (410 miles).

  3. What are the departure and arrival locations for buses traveling from Indianapolis to Des Moines?

    Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Jefferson/Trailways Depot, in Des Moines.

  4. What is the cheapest way to travel from Indianapolis to Des Moines?

    If you're on a budget, consider traveling by bus to Des Moines from Indianapolis; it tends to be more affordable. The ticket price for this bus starts at US$100, making this your best choice for this trip.

  5. How much does it cost to take the bus from Indianapolis to Des Moines?

    Taking the bus from Indianapolis to Des Moines costs on average US$147.

  6. Can I take an overnight bus from Indianapolis to Des Moines?

    Yes! Catch buses leaving from Indianapolis until 9:30pm and reaching Des Moines on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-23
US$101
04-24
No data
Today
No data
04-26
US$85
04-27
No data
04-28
No data
04-29
No data
04-30
No data
busbud logoThe cheapest trip from Indianapolis to Des Moines was searched and found on Apr 26, 2025 with a price of US$85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines, as early as possible.

You can expect to pay from US$85 to US$184 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$85 which is on 2025-04-26.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Des Moines.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to Des Moines will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Indianapolis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Des Moines

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