Bus Tickets from Indianapolis, IN to Des Moines, IA

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SatApr 26
from $85
SunApr 27
MonApr 28
TueApr 29
WedApr 30
ThuMay 1
FriMay 2
SatMay 3

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: April 27 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Indianapolis
    Departure location: Indianapolis
    Arrival time: April 26 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Burlington TrailwaysBurlington Trailways
    Vehicle: BusDuration:

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Bus Indianapolis to Des Moines: Trip Overview

Average ticket price$147
Average bus trip duration18h 5m
Number of daily buses3
Earliest bus departure7:10am
Distance410 miles (660 km)
Latest bus departure9:30pm

Indianapolis to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Des Moines.

Discover how much the bus trip from Indianapolis to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Indianapolis - Des Moines

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/22
$102
04/23
$101
Today
No data
04/25
No data
04/26
$85
04/27
No data
04/28
No data
04/29
No data
busbud logoThe cheapest trip from Indianapolis to Des Moines was searched and found on Apr 26, 2025 with a price of $85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines, as early as possible.

You can expect to pay from $85 to $184 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $85 which is on 2025-04-26.

Usually Burlington Trailways will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Indianapolis to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Indianapolis to Des Moines.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to Des Moines will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Indianapolis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Des Moines

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