Bus Tickets from San Luis Obispo, CA to San Francisco, CA

Find affordable bus tickets from San Luis Obispo, CA to San Francisco, CA with flexible options. Book your trip now

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FriApr 25
from US$50
SatApr 26
SunApr 27
MonApr 28
TueApr 29
WedApr 30
ThuMay 1
FriMay 2

Next departures to San Francisco

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: April 25 at
    Departure city: San Luis Obispo
    Departure location: San Luis Obispo
    Arrival time: April 25 at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: April 25 at
    Departure city: San Luis Obispo
    Departure location: San Luis Obispo
    Arrival time: April 25 at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Luis Obispo
    Departure location: San Luis Obispo
    Arrival time: April 25 at
    Destination city: San Francisco
    Destination location: 409 Townsend St, SF
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Luis Obispo
    Departure location: AMTRAK Station
    Arrival time: April 25 at
    Destination city: San Francisco
    Destination location: Mission St & Fremont St
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Luis Obispo
    Departure location: Cal Poly Vista Grande Dining Complex
    Arrival time: April 25 at
    Destination city: San Francisco
    Destination location: Mission St & Fremont St
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Last refresh of the prices: Today at 5:25 PM PDT.

Prices and availability are subject to change.

Accepted payments

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Bus San Luis Obispo to San Francisco: Trip Overview

Average Ticket PriceUS$47
Average Bus Trip Duration4h 20m
Number of daily buses1
Earliest bus departure1:50pm
Distance319 km
Latest bus departure4:10pm

San Luis Obispo to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from San Luis Obispo to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Luis Obispo to San Francisco from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from San Luis Obispo to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Luis Obispo - San Francisco

  1. How long is the trip from San Luis Obispo to San Francisco by bus?

    The bus ride from San Luis Obispo to San Francisco takes 4h 20m, on average. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 4h 20m.

  2. What is the travel distance from San Luis Obispo to San Francisco?

    San Luis Obispo and San Francisco are 326 km (202 miles) apart.

  3. What are the departure and arrival locations for buses traveling from San Luis Obispo to San Francisco?

    Buses departing from AMTRAK Station in San Luis Obispo will take you to Hyde/Beach (Fisherman's Wharf) in San Francisco.

  4. What is the cheapest way to get from San Luis Obispo to San Francisco?

    If you're on a budget, consider traveling by bus to San Francisco from San Luis Obispo; it tends to be more affordable. The ticket price for this bus starts at US$44, making this your best choice for this trip.

  5. How much does the bus ticket cost from San Luis Obispo to San Francisco?

    The bus from San Luis Obispo to San Francisco will cost you US$47, on average.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04-21
No data
04-22
No data
Today
No data
04-24
US$37
04-25
US$42
04-26
No data
04-27
No data
04-28
No data
busbud logoThe cheapest trip from San Luis Obispo to San Francisco was searched and found on Apr 24, 2025 with a price of US$37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to San Francisco, as early as possible.

You can expect to pay from US$37 to US$88 for a bus ticket from San Luis Obispo to San Francisco based on the last 2 days. You can expect to find the cheapest price for the trip at US$37 which is on 2025-04-24.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Luis Obispo to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Luis Obispo to San Francisco, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Luis Obispo to San Francisco that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Luis Obispo to San Francisco, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from San Luis Obispo to San Francisco?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Luis Obispo by bus?

Bus from San Luis Obispo to San Francisco

You can also go to San Francisco by train

Train from San Luis Obispo to San Francisco

Why choose Busbud?

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Popular Buses Connecting San Luis Obispo

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Popular Buses Connecting San Francisco

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