Find coaches from Guatemala City to Santa Ana

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Mon3 Feb
from US$88
Tue4 Feb
Wed5 Feb
Thu6 Feb
Fri7 Feb
from US$88
Sat8 Feb
Sun9 Feb
Mon10 Feb

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 7 February at
    Departure city: Guatemala City
    Departure location: Holiday Inn Guatemala City
    Arrival time: 7 February at
    Destination city: Santa Ana
    Destination location: Gasolinera Puma
    Operated by: GuategoGuatego
    Vehicle: BusDuration:
  • Departure time: 7 February at
    Departure city: Guatemala City
    Departure location: Holiday Inn Guatemala City
    Arrival time: 7 February at
    Destination city: Santa Ana
    Destination location: Gasolinera Puma
    Operated by: GuategoGuatego
    Vehicle: BusDuration:
  • Departure time: 7 February at
    Departure city: Guatemala City
    Departure location: Holiday Inn Guatemala City
    Arrival time: 7 February at
    Destination city: Santa Ana
    Destination location: Gasolinera Puma
    Operated by: GuategoGuatego
    Vehicle: BusDuration:

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Bus Guatemala City to Santa Ana: Trip Overview

Average ticket priceUS$50
Average bus trip duration4h
Number of daily buses6
Earliest bus departure06:00
Distance75 miles
Latest bus departure20:00

Guatemala City to Santa Ana buses

Busbud helps you find a bus from Guatemala City to Santa Ana. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Guatemala City to Santa Ana from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Santa Ana from Guatemala City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Guatemala City - Santa Ana

  1. What is the cheapest way to go from Guatemala City to Santa Ana?

    The prices typically range from US$25 to US$96 on this trip, with the average ticket costing US$50. The exact cost can vary based on different factors such as the time of travel, the day of the week, and the coach service provider. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long does it take to travel from Guatemala City to Santa Ana by bus?

    The coach journey between Guatemala City and Santa Ana lasts about 4h. If you're looking for the fastest trip, you can get there in just about 3h 40m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. When is the first coach from Guatemala City to Santa Ana?

    The first coach from Guatemala City to Santa Ana leaves at 06:00. Times and services may vary during weekends and holidays.

  4. How far is Santa Ana from Guatemala City by coach?

    The journey from Guatemala City to Santa Ana by coach covers an approximate distance of 78 miles (126 km).

  5. How many coaches travel from Guatemala City to Santa Ana each day?

    You'll find about 6 coaches operating on this route. Keep in mind the availability of coaches on this route may fluctuate depending on the day of the week.

  6. Is there a way to reach Santa Ana from Guatemala City without a car?

    You can reach Santa Ana from Guatemala City by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/01
US$88
31/01
US$88
Today
US$88
02/02
US$88
03/02
US$88
04/02
US$25
05/02
US$88
06/02
US$88
%{brand}s logoThe cheapest trip from Guatemala City to Santa Ana was searched and found on 4 Feb 2025 with a price of US$25

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guatemala City to Santa Ana as early as possible.

You can expect to pay from US$25 to US$104 for a bus ticket from Guatemala City to Santa Ana based on the last 2 days. You can expect to find the cheapest price for the trip at US$25, which is on 2025-02-04.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Guatemala City and Santa Ana!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Guatemala City to Santa Ana, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Guatemala City to Santa Ana.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Guatemala City to Santa Ana.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Guatemala City by bus?

Bus from Guatemala City to Santa Ana

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