Find coaches from Milan to Palermo

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Today28 Apr
from US$64
Tomorrow29 Apr
Wed30 Apr
from US$108
Thu1 May
from US$94
Fri2 May
Sat3 May
Sun4 May
Mon5 May

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 30 April at
    Departure city: Milan
    Departure location: Milan San Donato Bus Station
    Arrival time: 1 May at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: 30 April at
    Departure city: Milan
    Departure location: Lampugnano
    Arrival time: 1 May at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:

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Compare 2 ways to travel from Milan to Palermo

Bus
Average priceUS$44 - US$292Average duration1d 1h
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$116 - US$131Average duration16h 10m
37kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milan to Palermo

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 16 hours 10 minutes and with fares starting at just US$116, it presents an excellent value for a comfortable ride.

2carpool per day
16h 10mAverage duration
US$116Cheapest ticket
37kgCO₂ emissions

Bus Milan to Palermo: Trip Overview

Average ticket priceUS$103
Average bus trip duration1d 1h
Number of daily buses10
Earliest bus departure03:05
Distance572 miles
Latest bus departure23:50

Milan to Palermo Bus

Busbud helps you find a bus from Milan to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Milan to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Milan to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milan - Palermo

  1. What is the affordable way to go from Milan to Palermo?

    For coach travel from Milan to Palermo, ticket prices typically start at US$44 and can reach a maximum of US$292. These prices can change depending on factors like the date, the class and the coach company you choose. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long does it take to travel from Milan to Palermo by bus?

    The average duration for a trip from Milan to Palermo by coach is around 1d 1h. The fastest coach journey typically takes 21h. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. When is the first coach from Milan to Palermo?

    The first coach to Palermo from Milan departs at 03:05. Keep in mind that departure times might change on weekends and holidays.

  4. How far is Palermo from Milan by coach?

    The distance between Milan and Palermo by coach is approximately 551 miles (888 km).

  5. Is there a way to reach Palermo from Milan without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

  6. Is there am overnight coach from Milan to Palermo?

    Yes, you can find coaches leaving until 23:50 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/04
US$80
27/04
US$80
Today
US$64
29/04
US$90
30/04
US$108
01/05
US$94
02/05
US$94
03/05
US$94
busbud logoThe cheapest trip from Milan to Palermo was searched and found on 28 Apr 2025 with a price of US$64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milan to Palermo as early as possible.

You can expect to pay from US$64 to US$236 for a bus ticket from Milan to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$90, which is on 2025-04-29.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milan and Palermo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milan to Palermo, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Milan to Palermo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milan to Palermo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Milan to Palermo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milan by bus?

Bus from Milan to Palermo

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