Find coaches from Santa Ana, CA to San Diego, CA

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Today25 Apr
from US$38
Tomorrow26 Apr
from US$38
Sun27 Apr
from US$38
Mon28 Apr
from US$38
Tue29 Apr
from US$37
Wed30 Apr
Thu1 May
from US$38
Fri2 May
from US$38

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 26 April at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: 26 April at
    Destination city: San Diego
    Destination location: Cross Border Xpress CBX (USA)
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 26 April at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: 26 April at
    Destination city: San Diego
    Destination location: Cross Border Xpress CBX (USA)
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: 26 April at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: 26 April at
    Destination city: San Diego
    Destination location: Cross Border Xpress CBX (USA)
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: 26 April at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: 26 April at
    Destination city: San Diego
    Destination location: Cross Border Xpress CBX (USA)
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:
  • Departure time: 26 April at
    Departure city: Santa Ana
    Departure location: Santa Ana E Santa Ana Blvd
    Arrival time: 26 April at
    Destination city: San Diego
    Destination location: Cross Border Xpress CBX (USA)
    Operated by: Los LimousinesLos Limousines
    Vehicle: BusDuration:

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Bus Santa Ana to San Diego: Trip Overview

Average ticket priceUS$41
Average bus trip duration4h 35m
Number of daily buses14
Earliest bus departure00:45
Distance98 miles
Latest bus departure22:15

Santa Ana to San Diego Bus

Busbud helps you find a bus from Santa Ana to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Santa Ana to San Diego from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Santa Ana, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Santa Ana - San Diego

  1. How much does it cost to travel by coach from Santa Ana to San Diego?

    Coach ticket prices from Santa Ana to San Diego can start as low as US$40, though the average price for this trip is US$41. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long is a coach from Santa Ana to San Diego?

    The coach journey between Santa Ana and San Diego lasts about 4h 35m. If you're looking for the fastest trip, you can get there in just about 2h 5m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time is the first coach from Santa Ana to San Diego?

    The first coach from Santa Ana to San Diego leaves at 00:45. Times and services may vary during weekends and holidays.

  4. What's the distance between Santa Ana and San Diego by coach?

    The journey from Santa Ana to San Diego by coach covers an approximate distance of 83 miles (133 km).

  5. What is the best way to go from Santa Ana to San Diego without a car?

    You can reach San Diego from Santa Ana by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

  6. Can you go on a day trip from Santa Ana to San Diego?

    Absolutely, a day trip from Santa Ana to San Diego is totally possible. The round-trip by coach takes roughly 4h 10m. That gives you plenty of time to visit San Diego before making your way back to Santa Ana in the evening.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/04
US$38
24/04
US$38
Today
US$38
26/04
US$38
27/04
US$38
28/04
US$38
29/04
US$37
30/04
US$38
busbud logoThe cheapest trip from Santa Ana to San Diego was searched and found on 29 Apr 2025 with a price of US$37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana to San Diego as early as possible.

You can expect to pay from US$37 to US$38 for a bus ticket from Santa Ana to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$37, which is on 2025-04-29.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santa Ana and San Diego!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Ana to San Diego, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Santa Ana to San Diego.

Make a music playlist for your bus ride from Santa Ana to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Santa Ana by bus?

Bus from Santa Ana to San Diego

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Popular Buses Connecting Santa Ana

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Popular Buses Connecting San Diego

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