Bus Tickets from Durham, NC to Florence, SC

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TodayApr 4
TomorrowApr 5
SunApr 6
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TueApr 8
from $60
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FriApr 11

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 8 at
    Departure city: Durham
    Departure location: BP Gas Station
    Arrival time: April 8 at
    Destination city: Florence
    Destination location: 2301 W Lucas St.
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:

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Bus Durham to Florence: Trip Overview

Average ticket price$67
Average bus trip duration3h 40m
Number of daily buses1
Earliest bus departure4:20am
Distance134 miles (215 km)
Latest bus departure9:15pm

Durham to Florence Buses

Busbud helps you find a bus from Durham to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Durham to Florence from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Durham, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Durham - Florence

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/02
$60
04/03
No data
Today
No data
04/05
$49
04/06
No data
04/07
$60
04/08
$60
04/09
$60
busbud logoThe cheapest trip from Durham to Florence was searched and found on Apr 5, 2025 with a price of $49

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham to Florence, as early as possible.

You can expect to pay from $49 to $60 for a bus ticket from Durham to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at $49 which is on 2025-04-05.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Florence!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Durham to Florence, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Florence.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Florence.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Durham by bus?

Bus from Durham to Florence

You can also go to Florence by train

Train from Durham to Florence

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