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- This trip is recommended because it is: Cheapest + Fastest
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Bus Mendoza to Santiago: Trip Overview
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Mendoza to Santiago Bus
With Busbud, comparing and booking tickets for a bus from Mendoza to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make sure you can find a bus service from Mendoza to Santiago from the most reliable bus companies operating this trip.
Discover how much the bus trip from Mendoza to Santiago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Mendoza and Santiago?
Frequently asked questions for your trip Mendoza - Santiago
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mendoza to Santiago, as early as possible.
You can expect to pay from $31 to $52 for a bus ticket from Mendoza to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at $31 which is on 2025-04-25.
Usually CATA Internacional will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Mendoza to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mendoza to Santiago, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Mendoza to Santiago will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Mendoza to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top traveled bus routes
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Popular Buses Connecting Mendoza
Buses Leaving from Mendoza
- Bus from Mendoza to San Rafael
- Bus Mendoza - Las Cuevas
- Mendoza - Potrerillos
- Bus from Mendoza to La Paz
- Bus Mendoza - La Paz
- Mendoza - Malargüe
- Bus from Mendoza to Cacheuta Spa
- Bus Mendoza - San Juan
- Mendoza - Uspallata
- Bus from Mendoza to San Luis
- Bus Mendoza - La Rioja
- Mendoza - Los Penitentes
- Bus from Mendoza to Tilisarao
- Bus Mendoza - Rosario
- Mendoza - Neuquén
Buses Going to Mendoza
- Bus from San Rafael to Mendoza
- Bus Cacheuta Spa - Mendoza
- Uspallata - Mendoza
- Bus from Las Heras to Mendoza
- Bus General Alvear - Mendoza
- Malargüe - Mendoza
- Bus from San Juan to Mendoza
- Bus Neuquén - Mendoza
- San Luis - Mendoza
- Bus from Pocito to Mendoza
- Bus Rosario - Mendoza
- Potrerillos - Mendoza
- Bus from Puerto Madryn to Mendoza
- Bus La Plata - Mendoza
- San Miguel de Tucumán - Mendoza
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Antofagasta
- Bus Santiago - Valdivia
- Santiago - Talca
- Bus from Santiago to Chillan
- Bus Santiago - Mendoza
- Santiago - Los Angeles
- Bus from Santiago to Puerto Varas
- Bus Santiago - Santa Cruz
- Santiago - Casablanca
- Bus from Santiago to San Antonio
- Bus Santiago - Arica
- Santiago - Villarrica
- Bus from Santiago to Concon
- Bus Santiago - La Unión
- Santiago - Castro
Buses Going to Santiago
- Bus from Victoria to Santiago
- Bus Castro - Santiago
- Valdivia - Santiago
- Bus from San Felipe to Santiago
- Bus Antofagasta - Santiago
- La Serena - Santiago
- Bus from Pichilemu to Santiago
- Bus Vina del Mar - Santiago
- Puerto Varas - Santiago
- Bus from Arica to Santiago
- Bus Temuco - Santiago
- San Antonio - Santiago
- Bus from Santa Cruz to Santiago
- Bus Los Angeles - Santiago
- Chillan - Santiago
Popular routes in this country
- Bus from Buenos Aires to Puerto Iguazú
- Bus El Calafate - Perito Moreno
- El Calafate - Glaciar Perito Moreno
- Bus from El Calafate to Bariloche
- Bus Córdoba - Buenos Aires
- Bariloche - Mendoza
- Bus from Puerto Iguazú to Buenos Aires
- Bus Mendoza - Salta
- Buenos Aires - Rosario
- Bus from Bariloche to El Chaltén
- Bus Córdoba - Mendoza
- Salta - Mendoza
- Bus from Bariloche to El Calafate
- Bus Mendoza - Córdoba
- Mendoza - Bariloche
Popular international trips
- Travel in Argentina
- Bus to Mendoza
- Travel in Chile
- Bus to Santiago
- Mendoza to Santiago Buses