Trains tickets from Charleston (SC), US to Buffalo (NY)

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FriApr 25
from $374
SatApr 26
SunApr 27
MonApr 28
TueApr 29
WedApr 30
ThuMay 1
FriMay 2

Trains leaving Friday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 25 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: April 26 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 25 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: April 26 at
    Destination city: Buffalo
    Destination location: Exchange Street Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 25 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: April 26 at
    Destination city: Buffalo
    Destination location: Exchange Street Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 25 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: April 26 at
    Destination city: Buffalo
    Destination location: Exchange Street Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 25 at
    Departure city: Charleston
    Departure location: Charleston Station
    Arrival time: April 26 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Train Charleston to Buffalo: Trip Overview

Please note, this information is subject to change.

Average ticket price$272
Average train trip duration1d
Number of daily trains3
Earliest train departure9:34pm
Distance693 miles (1117 km)

Charleston to Buffalo Train

Busbud helps you find a train from Charleston to Buffalo. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.

We make it our job to connect you with the most dependable companies that offer train service from Charleston to Buffalo.

Discover how much the train trip from Charleston to Buffalo will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.

Frequently asked questions for your trip Charleston - Buffalo

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/21
$225
04/22
$311
Today
No data
04/24
No data
04/25
$374
04/26
No data
04/27
No data
04/28
No data
busbud logoThe cheapest trip from Charleston to Buffalo was searched and found on Apr 21, 2025 with a price of $225

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Charleston to Buffalo, as early as possible.

You can expect to pay from $225 to $1,679 for a train ticket from Charleston to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at $374 which is on 2025-04-25.

About Train Travel

Train Travel Tips

There are many train stations in the world, check it station pages on Busbud to get all information you need.

Whether you take a regional or high-speed train to Buffalo, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

With up to 30x less CO2 emissions for your train journey between Charleston and Buffalo, the train is an ecological alternative to flights or personal cars.

Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Charleston to Buffalo.

Did you know?

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!

Will you be returning to Charleston by train?

Train from Buffalo to Charleston

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Popular Trains Connecting Charleston

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