Compare 2 ways to go from Greenville to Chicago.
Busbud recommends taking the bus from Greenville to ChicagoAmong the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 21 hours 20 minutes and with fares starting at just $81, it presents an excellent value for a comfortable ride.
Train Greenville to Chicago: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5082 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $190.00
Greenville to Chicago Train
Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Greenville to Chicago.
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Whether it is train tickets or first class train tickets going to Chicago from Greenville, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Greenville - Chicago
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville to Chicago was searched and found on Apr 30, 2025 with a price of $202To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville to Chicago, as early as possible.
You can expect to pay from $202 to $1,416 for a train ticket from Greenville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $202 which is on 2025-04-30.
About Train Travel
Train Travel Tips
Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Greenville and Chicago is also a great way to travel to arrive in the city centre and save more time for your stay in Chicago.
Whether you take a regional or high-speed train to Chicago, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between Greenville and Chicago, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Make a music playlist for your train ride from Greenville to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
Top Traveled Train Routes
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