Compare 2 ways to go from Greenville to St Louis.
Busbud recommends taking the bus from Greenville to St LouisAmong the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 16 hours 20 minutes and with fares starting at just $99, it presents an excellent value for a comfortable ride.
Train Greenville to St Louis: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5079 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $417.00
Greenville to St Louis Train
With Busbud, comparing and booking tickets for a train from Greenville to St Louis is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
Train service from Greenville to St Louis will be provided by the most trusted companies.
Whether it is train tickets or first class train tickets going to St Louis from Greenville, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions for your trip Greenville - St Louis
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville to St Louis was searched and found on May 1, 2025 with a price of $276To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville to St Louis, as early as possible.
You can expect to pay from $276 to $1,579 for a train ticket from Greenville to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $276 which is on 2025-05-01.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Greenville to St Louis is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
No matter if you plan to take a regional or high-speed train to St Louis, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.
By choosing the train between Greenville and St Louis, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Create your own real life musical score by curating a personalized train travel playlist - the perfect accompaniment to your bus ride from Greenville to St Louis.
Did you know?
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
Top Traveled Train Routes
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Popular Trains Connecting Greenville
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Popular Trains Connecting St Louis
Trains Going to St Louis
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