Trains tickets from Indianapolis to Greenville (SC)

Discover your next train travel journey from Indianapolis to Greenville (SC) and book online with ease

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TomorrowApr 26
SunApr 27
from $182
MonApr 28
TueApr 29
WedApr 30
from $182
ThuMay 1
FriMay 2
SatMay 3

Trains leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 27 at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: April 28 at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 27 at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: April 28 at
    Destination city: Greenville
    Destination location: Greenville Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Indianapolis to Greenville.

Bus
Average Price$73 - $185Average Duration16h 35m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$155 - $251Average Duration1d 5h
58kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to Greenville

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 16 hours 35 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.

6bus per day
16h 35mAverage Duration
$73Cheapest ticket
16kgCO₂ emissions

Train Indianapolis to Greenville: Trip Overview

Please note, this information is subject to change.

Average ticket price$235
Average train trip duration1d 5h
Number of daily trains1
Earliest train departure12:15am
Distance396 miles (638 km)

Indianapolis to Greenville Train

With Busbud, comparing and booking tickets for a train from Indianapolis to Greenville is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.

We make sure you can find a train service from Indianapolis to Greenville from the most reliable train companies operating this trip.

Whether it is train tickets or first class train tickets going to Greenville from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Indianapolis - Greenville

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/23
No data
04/24
No data
Today
No data
04/26
No data
04/27
$182
04/28
No data
04/29
No data
04/30
$182
busbud logoThe cheapest trip from Indianapolis to Greenville was searched and found on Apr 27, 2025 with a price of $182

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Indianapolis to Greenville, as early as possible.

You can expect to pay from $182 to $1,136 for a train ticket from Indianapolis to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at $182 which is on 2025-04-27.

About Train Travel

Train Travel Tips

Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Indianapolis to Greenville is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.

Regional train? High-speed train? Whichever train to Greenville you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

By choosing the train between Indianapolis and Greenville, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Tune out to the fine sounds of your best music playlist on your train trip from Indianapolis to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.

Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.

The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers traveled aboard the Shinkansen at a speed of 210 km / h.

Will you be returning to Indianapolis by train?

Train from Greenville to Indianapolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Trains Connecting Indianapolis

Trains Leaving from Indianapolis

Popular Trains Connecting Greenville

Trains Going to Greenville