Find coaches from Cleveland, OH to Greenville, SC

Find affordable coach tickets from Cleveland, OH to Greenville, SC with flexible options. Book your journey now

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Tomorrow28 Apr
Tue29 Apr
Wed30 Apr
Thu1 May
Fri2 May
Sat3 May
Sun4 May
from US$132
Mon5 May

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 4 May at
    Departure city: Cleveland
    Departure location: Cleveland Bus Station
    Arrival time: 5 May at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 4 May at
    Departure city: Cleveland
    Departure location: Cleveland Bus Station
    Arrival time: 5 May at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 4 May at
    Departure city: Cleveland
    Departure location: Cleveland Bus Station
    Arrival time: 5 May at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Cleveland to Greenville

Bus
Average priceUS$99 - US$220Average duration22h
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$241 - US$329Average duration1d 3h
68kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Cleveland to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 22 hours and with fares starting at just US$99, it presents an excellent value for a comfortable ride.

3bus per day
22hAverage duration
US$99Cheapest ticket
19kgCO₂ emissions

Bus Cleveland to Greenville: Trip Overview

Average ticket priceUS$115
Average bus trip duration22h
Number of daily buses3
Earliest bus departure02:35
Distance462 miles
Latest bus departure17:20

Cleveland to Greenville Bus

Busbud helps you find a bus from Cleveland to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Cleveland to Greenville.

From cheap bus tickets to more luxurious buses travelling from Cleveland to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Cleveland - Greenville

  1. What is the cheapest way to go from Cleveland to Greenville?

    Coach ticket prices from Cleveland to Greenville can start as low as US$99, though the average price for this trip is US$115. These prices can change depending on factors like the date, the class and the coach company you choose. Keep in mind that booking tickets on the day of travel might result in higher prices.

  2. How long does it take to travel from Cleveland to Greenville by bus?

    The coach journey between Cleveland and Greenville lasts about 22h. If you're looking for the fastest trip, you can get there in just about 20h 55m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. When is the first coach from Cleveland to Greenville?

    The first coach from Cleveland to Greenville leaves at 02:35. Times and services may vary during weekends and holidays.

  4. How far is Greenville from Cleveland by coach?

    The journey from Cleveland to Greenville by coach covers an approximate distance of 461 miles (743 km).

  5. Is there a way to reach Greenville from Cleveland without flying?

    To travel from Cleveland to Greenville without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You also have the option of utilising carpooling services.

  6. Is there am overnight bus from Cleveland to Greenville?

    You can hop on coaches departing from Cleveland until 17:20 and reaching Greenville the following day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
25/04
US$92
26/04
No data
Today
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28/04
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29/04
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30/04
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busbud logoThe cheapest trip from Cleveland to Greenville was searched and found on 25 Apr 2025 with a price of US$92

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cleveland to Greenville as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Cleveland and Greenville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Cleveland to Greenville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Cleveland to Greenville that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Cleveland to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Cleveland to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Cleveland by bus?

Bus from Cleveland to Greenville

You can also go to Greenville by train

Train from Cleveland to Greenville

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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