Bus Tickets from Buffalo, NY to Charleston, SC

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TodayMar 10
TomorrowMar 11
WedMar 12
ThuMar 13
FriMar 14
SatMar 15
from $154
SunMar 16
from $202
MonMar 17

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: March 15 at
    Departure city: Buffalo
    Departure location: Buffalo (BUF) Airport
    Arrival time: March 17 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: March 15 at
    Departure city: Buffalo
    Departure location: Niagara Frontier Transportation Authority
    Arrival time: March 17 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus Buffalo to Charleston: Trip Overview

Average ticket price$149
Average bus trip duration1d 7h
Number of daily buses3
Earliest bus departure7:50am
Distance697 miles (1124 km)
Latest bus departure11:20pm

Buffalo to Charleston Buses

With Busbud, comparing and booking tickets for a bus from Buffalo to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Buffalo to Charleston.

From cheap bus tickets to more luxurious buses traveling from Buffalo to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Buffalo - Charleston

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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03/15
$154
%{brand}s logoThe cheapest trip from Buffalo to Charleston was searched and found on Mar 15, 2025 with a price of $154

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo to Charleston, as early as possible.

You can expect to pay from $154 to $225 for a bus ticket from Buffalo to Charleston based on the last 2 days. You can expect to find the cheapest price for the trip at $154 which is on 2025-03-15.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Buffalo to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Buffalo to Charleston.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Buffalo to Charleston that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Buffalo to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Buffalo to Charleston?

%{brand}s logoThe bus is the cheapest travel choice for this destination

Will you be returning to Buffalo by bus?

Bus from Buffalo to Charleston

You can also go to Charleston by train

Train from Buffalo to Charleston

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