Bus Tickets from Greenville, SC to Durham, NC

Find affordable bus tickets from Greenville, SC to Durham, NC with flexible options. Book your trip now

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TodayApr 27
TomorrowApr 28
TueApr 29
WedApr 30
from $33
ThuMay 1
FriMay 2
from $36
SatMay 3
SunMay 4

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: April 30 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: May 1 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: April 30 at
    Departure city: Greenville
    Departure location: Greenville, (SC - Taqueria Guadalajara #3)
    Arrival time: April 30 at
    Destination city: Durham
    Destination location: Durham
    Operated by: Tornado BusTornado Bus
    Vehicle: BusDuration:
  • Departure time: April 30 at
    Departure city: Greenville
    Departure location: 1111 Woodruff Road
    Arrival time: April 30 at
    Destination city: Durham
    Destination location: BP Gas Station
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: April 30 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: April 30 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 30 at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: April 30 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Greenville to Durham.

Average Price$39 - $137Average Duration4h 37m
8kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average Price$66 - $121Average Duration7h
31kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Greenville to Durham

Among the sustainable travel choices, the bus stands out as the good way to reach Durham. The journey takes about 4 hours 37 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.

9bus per day
4h 37mAverage Duration
$39Cheapest ticket
8kgCO₂ emissions

Bus Greenville to Durham: Trip Overview

Average ticket price$56
Average bus trip duration4h 37m
Number of daily buses9
Earliest bus departure7:45am
Distance208 miles (334 km)
Latest bus departure10:15pm

Greenville to Durham Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Durham.

We make sure you can find a bus service from Greenville to Durham from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Durham from Greenville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Greenville - Durham

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/25
$34
04/26
$34
Today
$34
04/28
No data
04/29
$33
04/30
$33
05/01
$33
05/02
$36
busbud logoThe cheapest trip from Greenville to Durham was searched and found on Apr 29, 2025 with a price of $33

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Durham, as early as possible.

You can expect to pay from $33 to $130 for a bus ticket from Greenville to Durham based on the last 2 days. You can expect to find the cheapest price for the trip at $33 which is on 2025-04-29.

Usually Expreso will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Durham but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Durham, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Greenville to Durham.

Make a music playlist for your bus ride from Greenville to Durham, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Greenville to Durham?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Greenville by bus?

Bus from Greenville to Durham

You can also go to Durham by train

Train from Greenville to Durham

Why choose Busbud?

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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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Popular Buses Connecting Greenville

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