Bus Tickets from Jacksonville, FL to Chicago, IL

Find affordable bus tickets from Jacksonville, FL to Chicago, IL with flexible options. Book your trip now

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TodayApr 28
from $195
TomorrowApr 29
WedApr 30
ThuMay 1
from $147
FriMay 2
SatMay 3
from $138
SunMay 4
MonMay 5

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: May 2 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: May 2 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: May 2 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: May 2 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Jacksonville to Chicago.

Bus
Average Price$94 - $294Average Duration1d 3h
34kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$121 - $2,526Average Duration1d 16h
126kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 3 hours 5 minutes and with fares starting at just $94, it presents an excellent value for a comfortable ride.

10bus per day
1d 3hAverage Duration
$94Cheapest ticket
34kgCO₂ emissions

Bus Jacksonville to Chicago: Trip Overview

Average ticket price$159
Average bus trip duration1d 3h
Number of daily buses10
Earliest bus departure8:05am
Distance852 miles (1374 km)
Latest bus departure9:45pm

Jacksonville to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Chicago.

We make it our job to connect you with the most dependable bus companies that cover bus service from Jacksonville to Chicago.

Discover how much the bus trip from Jacksonville to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Jacksonville - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/26
$161
04/27
No data
Today
$195
04/29
$126
04/30
No data
05/01
$147
05/02
No data
05/03
$138
busbud logoThe cheapest trip from Jacksonville to Chicago was searched and found on Apr 29, 2025 with a price of $126

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville to Chicago, as early as possible.

You can expect to pay from $126 to $223 for a bus ticket from Jacksonville to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2025-04-29.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Jacksonville to Chicago.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Jacksonville to Chicago will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Jacksonville to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Jacksonville to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville by bus?

Bus from Jacksonville to Chicago

You can also go to Chicago by train

Train from Jacksonville to Chicago

Why choose Busbud?

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