Bus Louisville to Knoxville: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Louisville to Knoxville Bus
Busbud helps you find a bus from Louisville to Knoxville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Louisville to Knoxville from the most reliable bus companies operating this trip.
Discover how much the bus trip from Louisville to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Louisville and Knoxville?
Frequently asked questions for your trip Louisville - Knoxville
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Louisville to Knoxville was searched and found on Apr 26, 2025 with a price of $56To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Louisville to Knoxville, as early as possible.
You can expect to pay from $56 to $58 for a bus ticket from Louisville to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2025-04-26.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Louisville and Knoxville!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Louisville to Knoxville, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Louisville to Knoxville will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Louisville to Knoxville.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top traveled bus routes
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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Louisville
Buses Leaving from Louisville
Buses Going to Louisville
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Bus Knoxville - Orlando
- Knoxville - Lexington
- Bus from Knoxville to Chicago
- Bus Knoxville - New York
- Knoxville - Miami
- Bus from Knoxville to Nashville
- Bus Knoxville - Atlanta
- Knoxville - Memphis
- Bus from Knoxville to Washington
- Bus Knoxville - Jackson
- Knoxville - Dallas
- Bus from Knoxville to Cincinnati
- Bus Knoxville - Philadelphia
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Bus Memphis - Knoxville
- Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Bus Tampa - Knoxville
- Richmond - Knoxville
- Bus from Atlanta to Knoxville
- Bus New York - Knoxville
- Dallas - Knoxville
- Bus from Greenville to Knoxville
- Bus Louisville - Knoxville
- Cookeville - Knoxville
- Bus from Washington to Knoxville
- Bus Lexington - Knoxville
- Baltimore - Knoxville