Bus Tickets from Philadelphia, PA to Greenville, SC

Find affordable bus tickets from Philadelphia, PA to Greenville, SC with flexible options. Book your trip now

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SatApr 26
from $91
SunApr 27
from $82
MonApr 28
TueApr 29
WedApr 30
from $83
ThuMay 1
from $85
FriMay 2
SatMay 3

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: April 27 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: April 27 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: April 27 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: April 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: April 27 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: April 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: April 27 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: April 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: April 27 at
    Departure city: Philadelphia
    Departure location: Schuylkill & Walnut
    Arrival time: April 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Philadelphia to Greenville: Trip Overview

Average ticket price$93
Average bus trip duration18h 20m
Number of daily buses13
Earliest bus departure3:10am
Distance529 miles (852 km)
Latest bus departure9:30pm

Philadelphia to Greenville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Philadelphia to Greenville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Greenville.

Discover how much the bus trip from Philadelphia to Greenville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Philadelphia - Greenville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/22
$90
04/23
$116
Today
$105
04/25
$93
04/26
$91
04/27
$82
04/28
$85
04/29
$80
busbud logoThe cheapest trip from Philadelphia to Greenville was searched and found on Apr 29, 2025 with a price of $80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to Greenville, as early as possible.

You can expect to pay from $80 to $187 for a bus ticket from Philadelphia to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at $80 which is on 2025-04-29.

Usually FlixBus Inc., Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Philadelphia to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Philadelphia to Greenville.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Philadelphia to Greenville will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Philadelphia to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

What's the cheapest way to go from Philadelphia to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia by bus?

Bus from Philadelphia to Greenville

You can also go to Greenville by train

Train from Philadelphia to Greenville

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