Bus Tickets from Port Saint Lucie, FL to Jacksonville, FL

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Bus Port Saint Lucie to Jacksonville: Trip Overview

Average ticket price$47
Average bus trip duration6h 5m
Number of daily buses2
Earliest bus departure1:40am
Distance225 miles (362 km)
Latest bus departure3:45pm

Port Saint Lucie to Jacksonville Bus

Busbud helps you find a bus from Port Saint Lucie to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Port Saint Lucie to Jacksonville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Port Saint Lucie, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Port Saint Lucie - Jacksonville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/23
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04/24
$32
Today
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04/26
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04/27
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busbud logoThe cheapest trip from Port Saint Lucie to Jacksonville was searched and found on Apr 24, 2025 with a price of $32

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Jacksonville, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Port Saint Lucie and Jacksonville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Port Saint Lucie to Jacksonville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Port Saint Lucie to Jacksonville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Port Saint Lucie to Jacksonville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Port Saint Lucie by bus?

Bus from Port Saint Lucie to Jacksonville

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