Bus Tickets from San Antonio, TX to Greenville, SC

Find affordable bus tickets from San Antonio, TX to Greenville, SC with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
SunApr 27
from $213
MonApr 28
TueApr 29
WedApr 30
ThuMay 1
FriMay 2
SatMay 3
SunMay 4

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 27 at
    Departure city: San Antonio
    Departure location: San Antonio Bus Station
    Arrival time: April 28 at
    Destination city: Greenville
    Destination location: 1116 Woodruff Rd
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Antonio to Greenville.

Bus
Average Price$113 - $253Average Duration1d 5h
41kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$234 - $248Average Duration1d 18h
148kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Antonio to Greenville

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 5 hours 55 minutes and with fares starting at just $113, it presents an excellent value for a comfortable ride.

4bus per day
1d 5hAverage Duration
$113Cheapest ticket
41kgCO₂ emissions

Bus San Antonio to Greenville: Trip Overview

Average ticket price$151
Average bus trip duration1d 5h
Number of daily buses4
Earliest bus departure1:05am
Distance1015 miles (1636 km)
Latest bus departure9:45pm

San Antonio to Greenville Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Antonio to Greenville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from San Antonio to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Antonio - Greenville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/23
No data
04/24
No data
Today
No data
04/26
$146
04/27
$213
04/28
$120
04/29
No data
04/30
No data
busbud logoThe cheapest trip from San Antonio to Greenville was searched and found on Apr 28, 2025 with a price of $120

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Greenville, as early as possible.

You can expect to pay from $120 to $213 for a bus ticket from San Antonio to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at $120 which is on 2025-04-28.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Antonio to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Antonio to Greenville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Antonio to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Antonio to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from San Antonio to Greenville?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Antonio by bus?

Bus from San Antonio to Greenville

You can also go to Greenville by train

Train from San Antonio to Greenville

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting San Antonio

Buses Leaving from San Antonio

Buses Going to San Antonio

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville