Trains tickets from St Louis to Chicago

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TueApr 29
from $39
WedApr 30
from $39
ThuMay 1
FriMay 2
from $56
SatMay 3
from $39
SunMay 4
from $32
MonMay 5
TueMay 6

Trains leaving Wednesday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 30 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 30 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 30 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 30 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: April 30 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: April 30 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to go from St Louis to Chicago.

Bus
Average Price$33 - $187Average Duration9h 40m
10kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average Price$30 - $98Average Duration5h 5m
38kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from St Louis to Chicago

Among the sustainable travel choices, the train stands out as the good way to reach Chicago. The journey takes about 5 hours 5 minutes and with fares starting at just $30, it presents an excellent value for a comfortable ride.

5train per day
5h 5mAverage Duration
$30Cheapest ticket
38kgCO₂ emissions

Train St Louis to Chicago: Trip Overview

Please note, this information is subject to change.

Average ticket price$42
Average train trip duration5h 5m
Number of daily trains5
Earliest train departure4:30am
Distance262 miles (422 km)
Latest train departure5:40pm

St Louis to Chicago Train

Busbud helps you find a train from St Louis to Chicago. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.

We make it our job to connect you with the most dependable companies that offer train service from St Louis to Chicago.

Whether it is train tickets or first class train tickets going to Chicago from St Louis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip St Louis - Chicago

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/25
$68
04/26
$56
Today
$68
04/28
$39
04/29
$39
04/30
$39
05/01
$39
05/02
$56
busbud logoThe cheapest trip from St Louis to Chicago was searched and found on Apr 28, 2025 with a price of $39

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from St Louis to Chicago, as early as possible.

You can expect to pay from $39 to $228 for a train ticket from St Louis to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $39 which is on 2025-04-28.

About Train Travel

Train Travel Tips

There are many train stations in the world, check it station pages on Busbud to get all information you need.

Whether you take a regional or high-speed train to Chicago, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

By choosing the train between St Louis and Chicago, you emit up to 30 times less CO2 than for the same journey made by plane or car!

Make a music playlist for your train ride from St Louis to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the deepest train stations in the world is in Kiev. Located at a depth of 105 m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60 m under the Great Wall of China!

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.

What's the cheapest way to go from St Louis to Chicago?

busbud logoThe train is the cheapest travel choice for this destination

The best way to travel between St Louis and Chicago is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $42 on average. If you're on a budget, you'll find cheap tickets from $30. If you're looking for the fastest way to get to Chicago, choose the train, as it will take you from St Louis to Chicago in about 5h 5m - that's the fastest way to get there!

Will you be returning to St Louis by train?

Train from Chicago to St Louis

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