Bus Chicago to Greenville: Trip Overview
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Chicago to Greenville Bus
Busbud helps you find a bus from Chicago to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Chicago to Greenville from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from Chicago to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Chicago and Greenville?
Frequently asked questions on the trip Chicago - Greenville
What is the cheapest way to go from Chicago to Greenville?
The prices typically range from US$82 to US$272 on this trip, with the average ticket costing US$103. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. Use Busbud to compare prices and amenities offered by different companies, ensuring you find the most favorable deals and promotions.
How long does it take to travel from Chicago to Greenville by bus?
The coach journey between Chicago and Greenville lasts about 20h 55m. If you're looking for the fastest trip, you can get there in just about 20h 10m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.
When is the first coach from Chicago to Greenville?
The first coach from Chicago to Greenville leaves at 05:45. Times and services may vary during weekends and holidays.
How far is Greenville from Chicago by coach?
The journey from Chicago to Greenville by coach covers an approximate distance of 561 miles (904 km).
Is there a way to reach Greenville from Chicago without flying?
To travel from Chicago to Greenville without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.
Is there am overnight bus from Chicago to Greenville?
You can hop on coaches departing from Chicago until 23:50 and reaching Greenville the following day. Make sure to bring a snack and a blanket to keep yourself feeling comfortable during the night.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Greenville was searched and found on 27 Apr 2025 with a price of US$90To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Greenville as early as possible.
You can expect to pay from US$90 to US$106 for a bus ticket from Chicago to Greenville based on the last 2 days. You can expect to find the cheapest price for the trip at US$90, which is on 2025-04-27.
Usually FlixBus Inc., Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Chicago and Greenville!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to Greenville, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to Greenville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Chicago to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
What's the cheapest way to go from Chicago to Greenville?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
Popular Buses Connecting Chicago
Buses Leaving from Chicago
Buses Going to Chicago
Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Spartanburg
- Coach Greenville - Charleston
- Bus Greenville - Miami
- Greenville - Greensboro
- Bus from Greenville to Chicago
- Coach Greenville - New Orleans
- Bus Greenville - Columbus
- Greenville - Washington
- Bus from Greenville to Atlanta
- Coach Greenville - Anderson
- Bus Greenville - Charlotte
- Greenville - New York
- Bus from Greenville to San Antonio
- Coach Greenville - Greenville
- Bus Greenville - Dallas
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Coach Burlington - Greenville
- Bus Nashville - Greenville
- Knoxville - Greenville
- Bus from Savannah to Greenville
- Coach Charlotte - Greenville
- Bus Miami - Greenville
- Washington - Greenville
- Bus from New York to Greenville
- Coach Birmingham - Greenville
- Bus Philadelphia - Greenville
- Los Angeles - Greenville
- Bus from Anderson to Greenville