Bus Tickets from Calama to Santiago

Find affordable bus tickets from Calama to Santiago with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayApr 25
TomorrowApr 26
from $35
SunApr 27
from $35
MonApr 28
from $35
TueApr 29
from $40
WedApr 30
from $40
ThuMay 1
from $35
FriMay 2

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: April 26 at
    Departure city: Calama
    Departure location: Calama
    Arrival time: April 27 at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja - San Francisco de Borja
    Operated by: Cikbus Elité / CikturCikbus Elité / Ciktur
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: April 26 at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: April 27 at
    Destination city: Santiago
    Destination location: San Borja
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Calama
    Departure location: Terminal de buses Calama
    Arrival time: April 27 at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja - San Francisco de Borja
    Operated by: Cikbus Elité / CikturCikbus Elité / Ciktur
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Calama
    Departure location: Av. Balmaceda
    Arrival time: April 27 at
    Destination city: Santiago
    Destination location: San Borja
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:
  • Departure time: April 26 at
    Departure city: Calama
    Departure location: Calama
    Arrival time: April 27 at
    Destination city: Santiago
    Destination location: Terminal de Buses San Borja
    Operated by: AndimarAndimar
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Calama to Santiago: Trip Overview

Average ticket price$47
Average bus trip duration21h 50m
Number of daily buses24
Earliest bus departure8:30am
Distance766 miles (1235 km)
Latest bus departure10:50pm

Calama to Santiago Bus

Busbud helps you find a bus from Calama to Santiago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Calama to Santiago will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santiago from Calama, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Calama - Santiago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/23
$49
04/24
$50
Today
$50
04/26
$35
04/27
$35
04/28
$35
04/29
$40
04/30
$40
busbud logoThe cheapest trip from Calama to Santiago was searched and found on Apr 26, 2025 with a price of $35

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Calama to Santiago, as early as possible.

You can expect to pay from $35 to $74 for a bus ticket from Calama to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-04-26.

Usually PlussChile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Calama and Santiago!

Much more than a mere vehicle taking you from Calama to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Calama to Santiago.

Make a music playlist for your bus ride from Calama to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Calama by bus?

Bus from Calama to Santiago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Calama

Buses Leaving from Calama

Buses Going to Calama

Popular Buses Connecting Santiago

Buses Leaving from Santiago

Buses Going to Santiago