Bus Tickets from Santiago to La Serena

Find affordable bus tickets from Santiago to La Serena with flexible options. Book your trip now

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TodayJan 23
from $16
TomorrowJan 24
from $8
SatJan 25
from $8
SunJan 26
from $8
MonJan 27
from $8
TueJan 28
from $8
WedJan 29
from $8
ThuJan 30
from $8

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: January 24 at
    Departure city: Santiago
    Departure location: Terminal de Buses San Borja - San Francisco de Borja
    Arrival time: January 24 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Buses RomaniBuses Romani
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: January 24 at
    Departure city: Santiago
    Departure location: San Borja
    Arrival time: January 25 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Serena MarSerena Mar
    Vehicle: BusDuration:
  • Departure time: January 24 at
    Departure city: Santiago
    Departure location: San Borja
    Arrival time: January 24 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: ParaviasParavias
    Vehicle: BusDuration:
  • Departure time: January 24 at
    Departure city: Santiago
    Departure location: Terminal de Buses San Borja - San Francisco de Borja
    Arrival time: January 24 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Cikbus Elité / CikturCikbus Elité / Ciktur
    Vehicle: BusDuration:
  • Departure time: January 24 at
    Departure city: Santiago
    Departure location: San Borja
    Arrival time: January 25 at
    Destination city: La Serena
    Destination location: Terminal de Buses La Serena
    Operated by: Pluss ChilePluss Chile
    Vehicle: BusDuration:

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Bus Santiago to La Serena: Trip Overview

Average ticket price$17
Average bus trip duration6h 30m
Number of daily buses1
Earliest bus departure5:50am
Distance247 miles (398 km)
Latest bus departure11:59pm

Santiago to La Serena Buses

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santiago to La Serena.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santiago to La Serena.

Discover how much the bus trip from Santiago to La Serena will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Santiago - La Serena

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/21
$14
01/22
$14
Today
$14
01/24
$8
01/25
$8
01/26
$8
01/27
$8
01/28
$8
%{brand}s logoThe cheapest trip from Santiago to La Serena was searched and found on Jan 26, 2025 with a price of $8

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago to La Serena, as early as possible.

You can expect to pay from $8 to $32 for a bus ticket from Santiago to La Serena based on the last 2 days. You can expect to find the cheapest price for the trip at $8 which is on 2025-01-26.

Usually PlussChile, Cikbus Elité / Ciktur will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santiago to La Serena but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Santiago to La Serena.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santiago to La Serena will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santiago to La Serena.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Santiago by bus?

Bus from Santiago to La Serena

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