Bus Tickets from Des Moines, IA to Jacksonville, FL

Find affordable bus tickets from Des Moines, IA to Jacksonville, FL with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Bus Des Moines to Jacksonville: Trip Overview

Average ticket price$208
Average bus trip duration1d 13h
Number of daily buses1
Earliest bus departure5:30am
Distance1022 miles (1647 km)

Des Moines to Jacksonville Bus

Busbud helps you find a bus from Des Moines to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Jacksonville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Des Moines - Jacksonville

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Jacksonville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Jacksonville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Jacksonville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Des Moines to Jacksonville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Des Moines by bus?

Bus from Des Moines to Jacksonville

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines

Popular Buses Connecting Jacksonville

Buses Leaving from Jacksonville

Buses Going to Jacksonville