Bus Tickets from Jacksonville, FL to Knoxville, TN

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Bus Jacksonville to Knoxville: Trip Overview

Average ticket price$114
Average bus trip duration13h 20m
Number of daily buses2
Earliest bus departure8:45am
Distance412 miles (663 km)
Latest bus departure9:45pm

Jacksonville to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Knoxville.

We make sure you can find a bus service from Jacksonville to Knoxville from the most reliable bus companies operating this trip.

Discover how much the bus trip from Jacksonville to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Jacksonville - Knoxville

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/26
$88
04/27
No data
Today
$105
04/29
$106
04/30
No data
05/01
No data
05/02
No data
05/03
$109
busbud logoThe cheapest trip from Jacksonville to Knoxville was searched and found on Apr 26, 2025 with a price of $88

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville to Knoxville, as early as possible.

You can expect to pay from $88 to $109 for a bus ticket from Jacksonville to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at $106 which is on 2025-04-29.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Knoxville, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Jacksonville to Knoxville will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Jacksonville to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Jacksonville by bus?

Bus from Jacksonville to Knoxville

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Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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