Bus Tickets from Medford, OR to San Francisco, CA

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Bus Medford to San Francisco: Trip Overview

Average ticket price$98
Average bus trip duration9h 45m
Number of daily buses2
Earliest bus departure8:20am
Distance318 miles (512 km)

Medford to San Francisco Bus

With Busbud, comparing and booking tickets for a bus from Medford to San Francisco is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Medford to San Francisco from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Medford to San Francisco, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Medford - San Francisco

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/23
$90
04/24
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04/26
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busbud logoThe cheapest trip from Medford to San Francisco was searched and found on Apr 23, 2025 with a price of $90

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Medford to San Francisco, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Medford to San Francisco.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Medford to San Francisco, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Medford to San Francisco that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Medford to San Francisco while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Medford by bus?

Bus from Medford to San Francisco

You can also go to San Francisco by train

Train from Medford to San Francisco

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