Bus Tickets from Orlando, FL to Durham, NC

Find affordable bus tickets from Orlando, FL to Durham, NC with flexible options. Book your trip now

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TodayApr 29
TomorrowApr 30
ThuMay 1
from $108
FriMay 2
SatMay 3
from $114
SunMay 4
from $95
MonMay 5
TueMay 6

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 1 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 2 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 1 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 2 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: May 1 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 2 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: May 1 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: May 2 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Orlando to Durham.

Bus
Average Price$75 - $186Average Duration18h 5m
22kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average Price$65 - $229Average Duration15h 40m
79kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from Orlando to Durham

Among the sustainable travel choices, the train stands out as the good way to reach Durham. The journey takes about 15 hours 40 minutes and with fares starting at just $65, it presents an excellent value for a comfortable ride.

1train per day
15h 40mAverage Duration
$65Cheapest ticket
79kgCO₂ emissions

Bus Orlando to Durham: Trip Overview

Average ticket price$112
Average bus trip duration18h 5m
Number of daily buses6
Earliest bus departure5:15am
Distance534 miles (861 km)
Latest bus departure10:40pm

Orlando to Durham Bus

Busbud helps you find a bus from Orlando to Durham. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Orlando to Durham.

Discover how much the bus trip from Orlando to Durham will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Orlando - Durham

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/27
No data
04/28
$162
Today
No data
04/30
$81
05/01
$108
05/02
$111
05/03
$114
05/04
$95
busbud logoThe cheapest trip from Orlando to Durham was searched and found on Apr 30, 2025 with a price of $81

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Durham, as early as possible.

You can expect to pay from $81 to $179 for a bus ticket from Orlando to Durham based on the last 2 days. You can expect to find the cheapest price for the trip at $81 which is on 2025-04-30.

Usually FlixBus Inc., Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Orlando and Durham!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Orlando to Durham.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Orlando to Durham will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Orlando to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Orlando by bus?

Bus from Orlando to Durham

You can also go to Durham by train

Train from Orlando to Durham

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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