Compare 2 ways to go from Philadelphia to St Louis.
Busbud recommends taking the bus from Philadelphia to St LouisAmong the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 1 day, 4 hours 35 minutes and with fares starting at just $74, it presents an excellent value for a comfortable ride.
Bus Philadelphia to St Louis: Trip Overview
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Philadelphia to St Louis Bus
Busbud helps you find a bus from Philadelphia to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Philadelphia to St Louis will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to St Louis from Philadelphia, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Philadelphia and St Louis?
Frequently asked questions for your trip Philadelphia - St Louis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia to St Louis was searched and found on May 1, 2025 with a price of $69To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to St Louis, as early as possible.
You can expect to pay from $69 to $209 for a bus ticket from Philadelphia to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-05-01.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and St Louis!
Much more than a mere vehicle taking you from Philadelphia to St Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Philadelphia to St Louis.
Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to St Louis while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
What's the cheapest way to go from Philadelphia to St Louis?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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