How can I travel from St Louis to Lexington without flying?

Taking the bus is the best way to travel to Lexington without flying. Traveling by bus offers a budget-friendly, secure, and easy way to go between the two cities. Taking a ride with other travelers through carpool services is an additional option to consider.

How long does it take to get to Lexington from St Louis by bus?

Traveling from St Louis to Lexington takes around 8h 45m on average, although the minimum time it takes to get there is 8h 45m with the fastest bus. This is the time it takes to travel the 313 miles (504 km) that separate the two cities.

What is the travel distance from St Louis to Lexington?

St Louis and Lexington are 313 miles (504 km) apart.

What are the departure and arrival stations when taking the bus from St Louis to Lexington?

The majority of buses traveling from St Louis to Lexington start their journey at Gateway Station and wind up at WJW Investments Bus Stop. These are the most popular pick-up and drop-off locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.

What is the most affordable way to go from St Louis to Lexington?

You can save a lot of money on your trip from St Louis to Lexington by choosing to travel by bus. With prices starting at $59, you won't find a more affordable way to get there.

How much are the bus tickets from St Louis to Lexington?

The bus ticket costs $79 on average. Over the last 30 days, the prices ranged between $59 and $124, so make sure to compare them to get the best option.

St Louis to Lexington (KY) Bus Tickets

FriApr 25

from $100

SatApr 26

SunApr 27

MonApr 28

TueApr 29

WedApr 30

ThuMay 1

FriMay 2

Cheap buses leaving Friday

One passenger / one way

This trip is recommended because it is: Cheapest + Fastest
Departure time: April 25 at 1:55pm
Departure city: St Louis
Departure location: Gateway Station
Arrival time: April 25 at 11:40pm
Destination city: Lexington
Destination location: WJW Investments Bus Stop
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 8h 45m
Departure time: April 25 at 2:30am
Departure city: St Louis
Departure location: Gateway Station
Arrival time: April 25 at 3:05pm
Destination city: Lexington
Destination location: WJW Investments Bus Stop
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 11h 35m

Accepted payments

Bus St Louis to Lexington: Trip Overview

Average ticket price$79

Average bus trip duration8h 45m

Number of daily buses2

Earliest bus departure2:30am

Distance312 miles (503 km)

Latest bus departure1:55pm

Compare bus companies

Greyhound

3.5/586,942 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound St Louis Lexington recent customer reviews

They wouldn’t help me and my clothes and bags are still on the bus and I’m trying to get my bags from bud in new york

Guy J.

July 30, 2022

US bus companies: FlixBus, Greyhound, Los Limousines, Tornado Bus, Valley Transit, New York Trailways, Wanda Coach

St Louis to Lexington Bus

Busbud helps you find a bus from St Louis to Lexington. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from St Louis to Lexington from the most reliable bus companies operating this trip.

Discover how much the bus trip from St Louis to Lexington will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Where are the popular stops in St Louis and Lexington?

Stops in St Louis

A - Gateway Station

Stops in Lexington

A - WJW Investments Bus Stop

B - Bus Stop Lexington

Frequently asked questions for your trip St Louis - Lexington

How can I travel from St Louis to Lexington without flying?
How long does it take to get to Lexington from St Louis by bus?
What is the travel distance from St Louis to Lexington?
What are the departure and arrival stations when taking the bus from St Louis to Lexington?
What is the most affordable way to go from St Louis to Lexington?
How much are the bus tickets from St Louis to Lexington?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

04/21

$88

04/22

$79

Today

$116

04/24

$82

04/25

$100

04/26

$71

04/27

$78

04/28

$67

The cheapest trip from St Louis to Lexington was searched and found on Apr 28, 2025 with a price of $67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Lexington, as early as possible.

You can expect to pay from $67 to $125 for a bus ticket from St Louis to Lexington based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-04-28.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St Louis and Lexington!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from St Louis to Lexington, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from St Louis to Lexington will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St Louis to Lexington.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to St Louis by bus?

Bus from St Louis to Lexington

Top traveled bus routes

Why choose Busbud?

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Bus Tickets from St Louis, MO to Lexington, KY