Bus Des Moines to St Louis: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Des Moines to St Louis Bus
Busbud helps you find a bus from Des Moines to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to St Louis.
Whether it is cheap bus tickets or more luxurious buses going to St Louis from Des Moines, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Des Moines and St Louis?
Frequently asked questions for your trip Des Moines - St Louis
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to St Louis was searched and found on Apr 26, 2025 with a price of $84To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to St Louis, as early as possible.
You can expect to pay from $84 to $84 for a bus ticket from Des Moines to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2025-04-26.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and St Louis!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Des Moines to St Louis.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to St Louis.
Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to St Louis while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Des Moines
Buses Leaving from Des Moines
- Bus from Des Moines to Iowa City
- Bus Des Moines - Washington
- Des Moines - Omaha
- Bus from Des Moines to Denver
- Bus Des Moines - Cedar Rapids
- Des Moines - Chicago
- Bus from Des Moines to Minneapolis
- Bus Des Moines - Ames
- Des Moines - Sioux Falls
- Bus from Des Moines to Kansas City
- Bus Des Moines - Dallas
- Des Moines - Madison
- Bus from Des Moines to Los Angeles
- Bus Des Moines - Rochester
- Des Moines - Granite Falls
Buses Going to Des Moines
- Bus from Washington to Des Moines
- Bus Chicago - Des Moines
- Minneapolis - Des Moines
- Bus from Las Vegas to Des Moines
- Bus Staples - Des Moines
- Iowa City - Des Moines
- Bus from Ames to Des Moines
- Bus Sioux City - Des Moines
- Kansas City - Des Moines
- Bus from Denver to Des Moines
- Bus Madison - Des Moines
- Dallas - Des Moines
- Bus from Omaha to Des Moines
- Bus Phoenix - Des Moines
- St Louis - Des Moines