Bus Tickets from San Francisco, CA to Santa Clara, CA

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TodayApr 25
from $23
TomorrowApr 26
SunApr 27
MonApr 28
TueApr 29
WedApr 30
ThuMay 1
FriMay 2

Next departures to Santa Clara

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: April 25 at
    Departure city: San Francisco
    Departure location: Mission St & Fremont St
    Arrival time: April 25 at
    Destination city: Santa Clara
    Destination location: Great America Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Francisco
    Departure location: Mission St & Fremont St
    Arrival time: April 25 at
    Destination city: Santa Clara
    Destination location: Santa Clara Transit Center
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Francisco
    Departure location: Mission St & Fremont St
    Arrival time: April 25 at
    Destination city: Santa Clara
    Destination location: Santa Clara Transit Center
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Francisco
    Departure location: Mission St & Fremont St
    Arrival time: April 25 at
    Destination city: Santa Clara
    Destination location: Santa Clara Transit Center
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: April 25 at
    Departure city: San Francisco
    Departure location: Mission St & Fremont St
    Arrival time: April 25 at
    Destination city: Santa Clara
    Destination location: Great America Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

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Bus San Francisco to Santa Clara: Trip Overview

Average ticket price$28
Average bus trip duration2h 47m
Number of daily buses15
Earliest bus departure5:15am
Distance377 miles (608 km)
Latest bus departure10:35pm

San Francisco to Santa Clara Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Francisco to Santa Clara.

We make sure you can find a bus service from San Francisco to Santa Clara from the most reliable bus companies operating this trip.

Discover how much the bus trip from San Francisco to Santa Clara will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip San Francisco - Santa Clara

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/23
No data
04/24
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Today
$23
04/26
No data
04/27
No data
04/28
No data
04/29
No data
04/30
No data
busbud logoThe cheapest trip from San Francisco to Santa Clara was searched and found on Apr 25, 2025 with a price of $23

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Francisco to Santa Clara, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Francisco to Santa Clara but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Francisco to Santa Clara, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from San Francisco to Santa Clara will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from San Francisco to Santa Clara, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to San Francisco by bus?

Bus from San Francisco to Santa Clara

You can also go to Santa Clara by train

Train from San Francisco to Santa Clara

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