Bus Tickets from Vermillion, SD to Des Moines, IA

Find affordable bus tickets from Vermillion, SD to Des Moines, IA with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMar 28
from $168
TomorrowMar 29
SunMar 30
MonMar 31
TueApr 1
WedApr 2
ThuApr 3
FriApr 4

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: March 28 at
    Departure city: Vermillion
    Departure location: Mcdonalds, N Dakota St
    Arrival time: March 29 at
    Destination city: Des Moines
    Destination location: Des Moines
    Operated by: Jefferson LinesJefferson Lines
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Vermillion to Des Moines: Trip Overview

Average ticket price$173
Average bus trip duration14h 35m
Number of daily buses2
Earliest bus departure8:55am
Distance189 miles (304 km)
Latest bus departure9:20pm

Vermillion to Des Moines Buses

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Vermillion to Des Moines.

We make it our job to connect you with the most dependable bus companies that cover bus service from Vermillion to Des Moines.

Discover how much the bus trip from Vermillion to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Vermillion - Des Moines

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/26
$168
03/27
No data
Today
$168
03/29
No data
03/30
No data
03/31
No data
04/01
No data
04/02
No data
%{brand}s logoThe cheapest trip from Vermillion to Des Moines was searched and found on Mar 26, 2025 with a price of $168

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Vermillion to Des Moines, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Vermillion to Des Moines but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Vermillion to Des Moines.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Vermillion to Des Moines will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Vermillion to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to Vermillion by bus?

Bus from Vermillion to Des Moines

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Popular Buses Connecting Vermillion

Buses Leaving from Vermillion

Buses Going to Vermillion

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines